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Key Documents

289876

Sigma-Aldrich

Ethylphosphonic acid

98%

Synonym(s):

P-Ethylphosphonic acid

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About This Item

Linear Formula:
C2H5P(O)(OH)2
CAS Number:
Molecular Weight:
110.05
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

mp

61-63 °C (lit.)

SMILES string

CCP(O)(O)=O

InChI

1S/C2H7O3P/c1-2-6(3,4)5/h2H2,1H3,(H2,3,4,5)

InChI key

GATNOFPXSDHULC-UHFFFAOYSA-N

General description

The synthesis of novel nucleotide analogs based on phosphonic acids from ethylphosphonic acid was studied.

Application

Ethylphosphonic acid was used as an internal standard in the determination of fosfomycin in human plasma.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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E V Efimtseva et al.
Bioorganicheskaia khimiia, 24(1), 16-20 (1998-04-29)
The synthesis of novel nucleotide analogues on the basis of ethylphosphonic acid was described. A rigid structural element, an amide or a double bond, was characteristics of the compounds synthesized. The antiviral and cytotoxic activities of these compounds were studied
Stefanie Klein et al.
Small (Weinheim an der Bergstrasse, Germany), 14(21), e1704111-e1704111 (2018-04-19)
Efficient magnetic reactive oxygen species (ROS) formation enhancing agents after X-ray treatment are realized by functionalizing superparamagnetic magnetite (Fe3 O4 ) and Co-ferrite (CoFe2 O4 ) nanoparticles with self-assembled monolayers (SAMs). The Fe3 O4 and CoFe2 O4 nanoparticles are synthesized
Adarsh Gandhi et al.
Biomedical chromatography : BMC, 32(6), e4214-e4214 (2018-02-21)
Extensive use and misuse of antibiotics over the past 50 years has contributed to the emergence and spread of antibiotic-resistant bacterial strains, rendering them as a global health concern. To address this issue, a dynamic in vitro hollow-fiber system, which mimics
Theodora A Papakondyli et al.
Journal of chromatography. A, 1332, 1-7 (2014-02-11)
An analytical method employing novel sample preparation and liquid chromatography coupled with atmospheric pressure chemical ionization mass spectrometric detection (LC-APCI/MS) was developed for the determination of fosfomycin in human plasma. Sample preparation involves derivatization through phase transfer catalysis (PTC) which
Jonna E Teikari et al.
The ISME journal, 12(6), 1619-1630 (2018-02-16)
Nodularia spumigena is a nitrogen-fixing cyanobacterium that forms toxic blooms in the Baltic Sea each summer and the availability of phosphorous is an important factor limiting the formation of these blooms. Bioinformatic analysis identified a phosphonate degrading (phn) gene cluster

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