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254134

Sigma-Aldrich

Ammonium chloride

99.998% trace metals basis

Synonym(s):

Salmiac

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About This Item

Linear Formula:
NH4Cl
CAS Number:
12125-02-9
Molecular Weight:
53.49
Beilstein:
4371014
EC Number:
235-186-4
MDL number:
MFCD00011420
UNSPSC Code:
12352302
eCl@ss:
38050207
PubChem Substance ID:
24855359
NACRES:
NA.23

vapor density

1.9 (vs air)

vapor pressure

1 mmHg ( 160.4 °C)

Assay

99.998% trace metals basis

form

powder

technique(s)

HPLC: suitable

impurities

≤25.0 ppm Trace Metal Analysis

mp

340 °C (subl.) (lit.)

SMILES string

N.Cl

InChI

1S/ClH.H3N/h1H;1H3

InChI key

NLXLAEXVIDQMFP-UHFFFAOYSA-N

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Application

Ammonium chloride (NH4Cl) is an ammonium salt which can be used for a variety of applications such as:
  • a catalyst for the one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones
  • a promoter in the multicomponent synthesis of pyrrolo[3,4-b]pyridine-5-one
  • a reagent to improve the hydrolysis rate of magnesium hydride for the generation of hydrogen
  • a reductant, which facilitates the recovery of metals that are utilized in lithium-ion batteries

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ammonium chloride-promoted four-component synthesis of pyrrolo [3, 4-b] pyridin-5-one
Janvier P, et al.
Journal of the American Chemical Society, 124(11), 2560-2567 (2002)
A sustainable process for metal recycling from spent lithium-ion batteries using ammonium chloride
Lv W, et al.
Waste Management (New York, N.Y.), 79(18), 545-553 (2018)
Ammonium chloride-catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones under solvent-free conditions.
Shaabani A, et al.
Tetrahedron Letters, 44(4), 857-859 (2003)
Hydrogen generation by hydrolysis of MgH2 and enhanced kinetics performance of ammonium chloride introducing
Huang M, et al.
International Journal of Hydrogen Energy, 40(18), 6145-6150 (2015)
Sewa Rijal et al.
Blood, 125(18), 2815-2824 (2015-03-05)
Phosphoinositide signaling regulates diverse cellular functions. Phosphoinositide-3 kinase (PI3K) generates PtdIns(3,4,5)P3 and PtdIns(3,4)P2, leading to the activation of proliferative and anti-apoptotic signaling pathways. Termination of phosphoinositide signaling requires hydrolysis of inositol ring phosphate groups through the actions of PtdIns(3,4,5)P3 3-phosphatase
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