Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

242934

Sigma-Aldrich

Ethyl iodoacetate

98%

Synonym(s):

Ethyl 2-iodoacetate, Ethyl monoiodoacetate, Iodoacetic acid ethyl ester

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
ICH2COOC2H5
CAS Number:
623-48-3
Molecular Weight:
214.00
Beilstein:
741934
EC Number:
210-796-3
MDL number:
MFCD00001081
UNSPSC Code:
12352100
PubChem Substance ID:
24854592
NACRES:
NA.22

Quality Level

200

Assay

98%

refractive index

n20/D 1.503 (lit.)

bp

179-180 °C (lit.)

density

1.808 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CCOC(=O)CI

InChI

1S/C4H7IO2/c1-2-7-4(6)3-5/h2-3H2,1H3

InChI key

MFFXVVHUKRKXCI-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Ethyl iodoacetate was used in the synthesis of trans-2,3-disubstituted indolines by reacting with 1-azido-2-allylbenzene derivatives via a diastereoselective radical cascade.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H300,H314

Hazard Classifications

Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

170.6 °F - closed cup

Flash Point(C)

77 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

François Brucelle et al.
The Journal of organic chemistry, 78(12), 6245-6252 (2013-06-01)
The preparation of trans-2,3-disubstituted indolines from 1-azido-2-allylbenzene derivatives via a diastereoselective radical cascade using ethyl iodoacetate and triethylborane is described. Further lactamization afforded substituted benzopyrrolizidinones with excellent diastereomeric ratios. The radical cascade/lactamization sequence was efficiently applied to the synthesis of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service