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19240

Sigma-Aldrich

Butyramide

≥98.0% (T)

Synonym(s):

Amide C4

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About This Item

Linear Formula:
CH3CH2CH2CONH2
CAS Number:
541-35-5
Molecular Weight:
87.12
Beilstein:
1361528
EC Number:
208-776-4
MDL number:
MFCD00041894
UNSPSC Code:
12352100
PubChem Substance ID:
57647787
NACRES:
NA.22

Assay

≥98.0% (T)

mp

114-116 °C

solubility

alcohol: soluble(lit.)
diethyl ether: slightly soluble(lit.)
water: soluble(lit.)

SMILES string

CCCC(N)=O

InChI

1S/C4H9NO/c1-2-3-4(5)6/h2-3H2,1H3,(H2,5,6)

InChI key

DNSISZSEWVHGLH-UHFFFAOYSA-N

Gene Information

rat ... Ggt1(116568)

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Application

Butyramide was used in the synthesis of hydroxamic acids, electrorheological fluids and β-amodoorganotin compounds. It was used as substrate of (+)-γ-lactamase to develop a microreactor to study enzyme stability, activity, kinetics and substrate specificity.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R A Norman et al.
The Journal of biological chemistry, 275(39), 30660-30667 (2000-07-13)
Expression of the amidase operon of Pseudomonas aeruginosa is controlled by AmiC, the ligand sensor and negative regulator, and AmiR the transcription antitermination factor activator. We have titrated out AmiC repression activity in vivo by increased AmiR production in trans
Rajendra Singh et al.
Bioprocess and biosystems engineering, 41(8), 1225-1232 (2018-05-12)
Butyramide is a commodity chemical having wide range of applications from material science to biological sciences including synthesis of therapeutic drugs, hydroxamic acids, and electrorheological fluids. The nitrile hydratase protein of Bacillus sp. APB-6 was explored to develop an efficient
B P O'Hara et al.
Protein engineering, 13(2), 129-132 (2000-03-10)
The AmiC protein in Pseudomonas aeruginosa is the negative regulator and ligand receptor for an amide-inducible aliphatic amidase operon. In the wild-type PAC1 strain, amidase expression is induced by acetamide or lactamide, but not by butyramide. A mutant strain of
P Rocchi et al.
Anticancer research, 18(2A), 1099-1103 (1998-06-06)
Butyric acid has been shown in vitro to produce cytodifferentiation of a wide variety of neoplastic cells. The potential clinical use of this compound as a therapeutic agent is limited by its rapid metabolism. This has led to the examination
Gabor Butora et al.
Bioorganic & medicinal chemistry letters, 16(18), 4715-4722 (2006-07-28)
A systematic examination of the central aromatic portion of the lead (2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-(4-fluorophenyl)-4-(1'H-spiro[indene-1,4'-piperidin]-1'-yl)butanamide (9) led to the discovery of a novel class of CCR2 receptor antagonists, which carry small alicyclic groups such as cyclopropyl, cylobutyl, or cyclopropylmethyl attached at C2 of
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