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144657

Sigma-Aldrich

Trifluoroacetamide

97%

Synonym(s):

2,2,2-Trifluoroacetamide

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About This Item

Linear Formula:
CF3CONH2
CAS Number:
354-38-1
Molecular Weight:
113.04
Beilstein:
1753625
EC Number:
206-559-9
MDL number:
MFCD00008008
UNSPSC Code:
12352100
PubChem Substance ID:
24848677
NACRES:
NA.22

Assay

97%

form

solid

bp

162.5 °C (lit.)

mp

65-70 °C (lit.)

SMILES string

NC(=O)C(F)(F)F

InChI

1S/C2H2F3NO/c3-2(4,5)1(6)7/h(H2,6,7)

InChI key

NRKYWOKHZRQRJR-UHFFFAOYSA-N

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General description

Trifluoroacetamide is a good quencher of tryptophan fluorescence.

Application

Trifluoroacetamide was used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Melody Anne de Laat et al.
PloS one, 13(6), e0200070-e0200070 (2018-06-30)
Hyperinsulinemia is a major risk factor for equine laminitis, a debilitating and painful foot condition. Sweet taste receptor (T1R2/3) inhibitors have been used to reduce the insulin and glucose responses to oral carbohydrates in other species. However, their effect in
P Midoux et al.
Biochimica et biophysica acta, 801(1), 16-25 (1984-09-07)
Trifluoroacetamide was found to be a good quencher of tryptophan fluorescence, and the quenching was shown to proceed via both a dynamic and a static process. The respective quenching constants were determined by the measurement of the decrease of the
Simona Grasso et al.
Foods (Basel, Switzerland), 8(12) (2019-12-19)
The objective of this study was to develop a precise and accurate method to quantify cholesterol in turkey meat products using relative response factors, based on a modification of a previously published method for plant sterols determination. Validation was performed
Shivani Pasricha et al.
Frontiers in cellular and infection microbiology, 7, 368-368 (2017-09-02)
Fungal infections are an increasing public health problem, particularly in immunocompromised individuals. While these pathogenic fungi show polyphyletic origins with closely related non-pathogenic species, many undergo morphological transitions to produce pathogenic cell types that are associated with increased virulence. However
Fiona N Mumoki et al.
Scientific reports, 8(1), 7701-7701 (2018-05-26)
Social cohesion in social insect colonies can be achieved through the use of chemical signals whose production is caste-specific and regulated by social contexts. In honey bees, queen mandibular gland pheromones (QMP) maintain reproductive dominance by inhibiting ovary activation and
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