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Key Documents

114480

Sigma-Aldrich

Cresol Red sodium salt

indicator grade

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About This Item

Empirical Formula (Hill Notation):
C21H17NaO5S
CAS Number:
Molecular Weight:
404.41
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

grade

indicator grade

form

solid

mp

250 °C (dec.) (lit.)

solubility

H2O: 1 mg/mL

λmax

425 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].Cc1cc(ccc1O)\C(=C2/C=CC(=O)C(C)=C2)c3ccccc3S([O-])(=O)=O

InChI

1S/C21H18O5S.Na/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26;/h3-12,22H,1-2H3,(H,24,25,26);/q;+1/p-1/b21-16-;

InChI key

GBXGEGUVARLBPB-PLMZOXRSSA-M

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Application

Cresol Red has been used for checking the immobilized carbonic anhydrase-catalyzed reactions. It has also been used in the loading buffer for MHC (major histocompatibility complex) class I typing through PCR.

Biochem/physiol Actions

Cresol Red is used as a pH indicator.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Paula C A Jerónimo et al.
The Analyst, 130(8), 1190-1197 (2005-07-16)
An optical biosensor based on immobilised carbonic anhydrase and its application to the determination of the anti-glaucoma agent acetazolamide by enzyme inhibition measurements, is described. The enzyme and a pH indicator dye, cresol red, were physically immobilised in overlapped sol-gel
K Schilling et al.
Clinical chemistry, 39(2), 251-256 (1993-02-01)
If buffer/indicator systems are used as optical thermometers in multicuvettes, the temperature resolution is limited by errors of optical measurements produced mainly by variations of pathlength and blank transmittance of the wells. Theoretical and practical approaches show that, in multicuvettes
K Elamrani et al.
Biochimica et biophysica acta, 727(1), 22-30 (1983-01-05)
The kinetics of H+/OH- diffusion across dimyristoyl phosphatidic acid bilayer membranes was measured by following the absorbance of the pH-sensitive indicator Cresol red (o-cresolsulfonphthalein) entrapped in single lamellar vesicles after rapidly changing the external pH in a stopped-flow apparatus. The
R Schubert
Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. Serie B, Umwelthygiene, Krankenhaushygiene, Arbeitshygiene, praventive Medizin, 187(3), 266-268 (1989-02-01)
A new medium is described for the isolation of P. aeruginosa organisms which have been damaged by chlorination. This medium utilises the fact that with arginine. P. aeruginosa produces a strongly alkaline reaction resulting in an easily identified colour change
M Swati et al.
Analytica chimica acta, 676(1-2), 68-74 (2010-08-31)
An optical biosensing scheme based on urease encapsulated calcium alginate microspheres which are coated with polyelectrolyte nanofilms predominantly composed of cresol red (CR) dye is demonstrated in this paper. The dye molecules within the nanofilms are deposited via the layer-by-layer

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