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SCP0109

Sigma-Aldrich

Cathepsin D Substrate

≥95% (HPLC), lyophilized

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About This Item

Empirical Formula (Hill Notation):
C49H55N9O7
Molecular Weight:
882.02
UNSPSC Code:
12352202
NACRES:
NA.32

product name

Cathepsin D Substrate,

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥85%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Bz-Arg-Gly-Phe-Phe-Pro-4M2NA

General description

Cathepsin D Substrate is a peptide with Bz-Arg-Gly-Phe-Phe-Pro-4M2NA sequence.

Application

Cathepsin D Substrate has been used in cathepsin D enzymatic assays with Dictyostelium, midgut samples of beetles Stromatium fulvum (Villers) and of P. versicolora.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Robert J Huber et al.
Cellular signalling, 58, 79-90 (2019-02-17)
Mutations in CLN3 cause a juvenile form of neuronal ceroid lipofuscinosis (NCL). This devastating neurological disorder, commonly known as Batten disease, is currently untreatable due to a lack of understanding of the physiological role of the protein. Recently, work in
Digestive proteolytic profile in Stromatium fulvum Villers (Coleoptera: Cerambycidae)
ZIBAEE A, et al.
Romanian Journal of Biochemistry, 51, 17-30 (2014)
Tonyia Eaves-Pyles et al.
PloS one, 6(9), e24869-e24869 (2011-09-29)
Bacteria release flagellin that elicits innate responses via Toll-like receptor 5 (TLR5). Here, we investigated the fate of apically administrated full length flagellin from virulent and avirulent bacteria, along with truncated recombinant flagellin proteins in intestinal epithelial cells and cellular
Proteolytic activity in Plagiodera versicolora Laicharting (Coleoptera: Chrysomelidae): Characterization of digestive proteases and effect of host plants
Zibaee A and Hajizadeh J
Journal of Asia-Pacific Entomology, 16, 329-334 (2013)
Hong-Ye Wan et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 5(3), 1700585-1700585 (2018-03-30)
Targeting protein degradation is recognized as a valid approach to cancer therapy. The ubiquitin-proteasome system (UPS) and the autophagy-lysosome pathway are two major pathways for intracellular protein degradation. Proteasome inhibitors such as bortezomib are clinically approved for treating malignancies, but

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