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R2886

Sigma-Aldrich

Resorufin β-D-glucuronide sodium salt

β-glucuronidase substrate, ≥90%, powder

Synonym(s):

3-Phenoxazone 7-(β-D-glucuronide)

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About This Item

Linear Formula:
C18H14NO9Na
CAS Number:
Molecular Weight:
411.29
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

product name

Resorufin β-D-glucuronide sodium salt, ≥90%

Assay

≥90%

form

powder

solubility

water: 0.5 mg/mL, clear to slightly hazy, orange

storage temp.

−20°C

SMILES string

[Na].OC1C(OC(C(O)C1O)C(O)=O)Oc2ccc3N=C4C=CC(=O)C=C4Oc3c2

InChI

1S/C18H15NO9.Na.H/c20-7-1-3-9-11(5-7)27-12-6-8(2-4-10(12)19-9)26-18-15(23)13(21)14(22)16(28-18)17(24)25;;/h1-6,13-16,18,21-23H,(H,24,25);;

InChI key

AESIKFVBGSSFKP-UHFFFAOYSA-N

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Application

Resorufin β-D-glucuronide sodium salt has been used for testing enzymatic activities.

Biochem/physiol Actions

Resorufin β-D-glucuronide serves as a substrate for β-glucuronidase enzyme. It is considered as an internal hydrolysis indicator for enzyme action. Resorufin β-D-glucuronide possesses a high extinction coefficient.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Internal Hydrolysis Indicator for Sample Specific Monitoring of beta-Glucuronidase Activity
Taylor LL, et al.
Journal of Analytical Toxicology, 41(5), 407-411 (2017)
Synthesis and application of resorufin beta-d-glucuronide, a low-cost chromogenic substrate for detecting Escherichia coli in drinking water
Magro G, et al.
Environmental Science & Technology, 48(16), 9624-9631 (2014)
Bi-Enzymatic Embolization Beads for Two-Armed Enzyme-Prodrug Therapy
Olesen MTJ, et al.
Advances in Therapy, 1(4), 1800023-1800023 (2018)

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