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H2393

Sigma-Aldrich

HEPES sodium salt hydrate

≥99% (titration)

Synonym(s):

N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid) hemisodium salt

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About This Item

Linear Formula:
C8H17N2O4SNa
CAS Number:
75277-39-3
Molecular Weight:
260.29
EC Number:
278-169-7
MDL number:
MFCD00150464
UNSPSC Code:
12161700
PubChem Substance ID:
24895161

Assay

≥99% (titration)

form

powder

useful pH range

6.8-8.2

 

7.5

pKa 

7.5

solubility

water: 500 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

SMILES string

O.[Na+].OCCN1CCN(CC1)CCS([O-])(=O)=O

InChI

1S/C8H18N2O4S.Na.H2O/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;;/h11H,1-8H2,(H,12,13,14);;1H2/q;+1;/p-1

InChI key

ZNJHFNUEQDVFCJ-UHFFFAOYSA-M

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Christian Giaume et al.
Methods in molecular biology (Clifton, N.J.), 814, 283-303 (2011-12-07)
A typical feature of astrocytes is their high level of connexin expression. These membrane proteins constitute the molecular basis of two types of channels: gap junction channels that allow direct cytoplasm-to-cytoplasm communication and hemichannels that provide a pathway for exchanges
Tina Vognsen et al.
Biochemical and biophysical research communications, 420(1), 188-192 (2012-03-15)
The crystal structure of the NTF2-like domain of the Drosophila homolog of Ras GTPase SH3 Binding Protein (G3BP), Rasputin, was determined at 2.7Å resolution. The overall structure is highly similar to nuclear transport factor 2: It is a homodimer comprised
Jihye Park et al.
The Analyst, 137(19), 4411-4414 (2012-08-07)
We have developed a quickly responsive, and specific fluorescent assay for the detection of Au(III) on the basis of the formation of gold nanoparticles in the presence of HEPES, which cleave the C-I bond of I-BODIPY 1 to yield the
S Hugel et al.
British journal of pharmacology, 166(8), 2402-2416 (2012-03-29)
Artificial buffers such as HEPES are extensively used to control extracellular pH (pH(e) ) to investigate the effect of H(+) ions on GABA(A) receptor function. In neurones cultured from spinal cord dorsal horn (DH), dorsal root ganglia (DRG) and cerebellar
Megan Garvey et al.
Biochemical and biophysical research communications, 409(3), 385-388 (2011-05-18)
The oligomerization of Aβ peptide into amyloid fibrils is a hallmark of Alzheimer's disease. Due to its biological relevance, phosphate is the most commonly used buffer system for studying the formation of Aβ and other amyloid fibrils. Investigation into the
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