Skip to Content
Merck
All Photos(3)

Documents

271R-2

Sigma-Aldrich

Inhibin, alpha (MRQ-63) Rabbit Monoclonal Antibody

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

UNSPSC Code:
12352203

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

MRQ-63, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (271R-24)
vial of 0.1 mL concentrate Research Use Only (271R-24-RUO)
vial of 0.5 mL concentrate (271R-25)
vial of 1.0 mL concentrate (271R-26)
vial of 1.0 mL concentrate Research Use Only (271R-26-RUO)
vial of 1.0 mL pre-dilute Research Use Only (271R-27-RUO)
vial of 1.0 mL pre-dilute ready-to-use (271R-27)
vial of 7.0 mL pre-dilute ready-to-use (271R-28)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (271R-28-RUO)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

isotype

IgG

control

adrenal cortex

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... INHA(3623)

General description

Inhibin is a peptide hormone that inhibits FSH secretion from the pituitary. Inhibin is a dimer that consists of an alpha and beta subunit. In normal tissue, anti-inhibin alpha labels granulosa cells of the ovary, sertoli and Leydig cells of the testis, and the zona reticularis of the adrenal cortex. Anti-inhibin alpha has demonstrated utility in the identification of sex cord-stromal tumors and adrenal cortical tumors.

Quality


IVD
IVD
IVD
RUO

Linkage

Inhibin, alpha Positive Control Slides, Product No. 271S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

Download the latest released IFU
Note: This IFU may not apply to your specific product lot.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

W G McCluggage et al.
Journal of clinical pathology, 51(2), 114-116 (1998-05-29)
To investigate the immunohisto-chemical staining of normal, hyperplastic, and neoplastic adrenal cortex with a monoclonal antibody against alpha inhibin. Also, to determine whether immunostaining with this antibody is useful in differentiating between adrenal cortical neoplasms and other tumours involving the
C Guerrieri et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 17(3), 266-271 (1998-07-10)
We have investigated the use of inhibin and cytokeratin-7 (CK-7) in distinguishing endometrioid ovarian carcinomas (both typical and sex cord-like) form granulosa cell and Sertoli cell-containing ovarian tumors. Immunohistochemical staining with inhibin, CK-7, and epithelial membrane antigen (EMA) was performed
K A Iczkowski et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11(8), 774-779 (1998-08-28)
We compared the expression of inhibin A, chromogranin, synaptophysin, S-100 protein, cytokeratins AE1/AE3, 7, and 20, and estrogen and progesterone receptors in testicular sex cord-stromal tumors: 11 Sertoli cell tumors, 3 Sertoli cell adenomas (nodules), 26 benign Leydig cell tumors
F Kommoss et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 11(7), 656-664 (1998-08-04)
We investigated 203 ovarian tumors and tumor-like lesions for inhibin expression using a monoclonal anti-inhibin alpha antibody. Inhibin was present in the tumor cells in all 14 primary adult granulosa cell tumors (4 luteinized) plus 3 metastatic, all 10 primary
L M Munro et al.
The Journal of endocrinology, 161(2), 341-347 (1999-05-13)
Inhibins and activins are dimeric proteins of the transforming growth factor-beta superfamily which have been shown to be expressed in the adrenal cortex. Recent studies have suggested a role for these peptides in the pathogenesis and/or function of adrenal tumours.
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service