Skip to Content
Merck
All Photos(2)

Key Documents

33816

Supelco

Toltrazuril sulfone

VETRANAL®, analytical standard

Synonym(s):

1-Methyl-3-{3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl}-1,3,5-triazine-2,4,6(1H,3H,5H)-trione

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C18H14F3N3O6S
CAS Number:
Molecular Weight:
457.38
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CN1C(=O)NC(=O)N(C1=O)c2ccc(Oc3ccc(cc3)S(=O)(=O)C(F)(F)F)c(C)c2

InChI

1S/C18H14F3N3O6S/c1-10-9-11(24-16(26)22-15(25)23(2)17(24)27)3-8-14(10)30-12-4-6-13(7-5-12)31(28,29)18(19,20)21/h3-9H,1-2H3,(H,22,25,26)

InChI key

VBUNOIXRZNJNAD-UHFFFAOYSA-N

General description

Toltrazuril sulfone is an antiprotozoal agent, which belongs to the group of triazines. It is highly effective against apicomplexan group of organisms.

Application

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Toltrazuril sulfone may be used as a reference standard in the determination of toltrazuril sulfone in food samples using fast liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS).

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Detection, quantifications and pharmacokinetics of toltrazuril sulfone ([TM="Ponazuril"]) in cattle.
Dirikolu L, et al.
Journal of Veterinary Pharmacology and Therapeutics, 32(3), 280-288 (2009)
Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs.
Lim HJ, et al.
The Journal of Veterinary Medical Science, 72(8), 1085-1087 (2010)
Anna Martínez-Villalba et al.
Analytical and bioanalytical chemistry, 397(7), 2893-2901 (2010-07-27)
In this work a fast liquid chromatography (LC)-tandem mass spectrometry (MS/MS) method was developed for the analysis of toltrazuril, a coccidiostatic drug, and its metabolites in meat food products. The applicability of atmospheric pressure chemical ionization (APCI) and heated electrospray
Janis Rusko et al.
Journal of pharmaceutical and biomedical analysis, 164, 402-412 (2018-11-16)
A new sensitive and selective multi-residue method based on liquid chromatography - Orbitrap high resolution mass spectrometry (LC-Orbitrap-HRMS) was developed and validated for the determination of 17 anticoccidials in poultry and eggs. Instrumental parameters were optimized by the means of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service