8.41359

Triisopropylsilane

for synthesis

• Synonym(s): Triisopropylsilane
• Linear Formula: ((CH₃)₂CH)₃SiH
• CAS Number: 6485-79-6
• Molecular Weight: 158.36
• MDL number: MFCD00009657
• UNSPSC Code: 12352103
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: ≥98.0% (GC)
• form: liquid
• bp: 84-85 °C/46.7 hPa
• transition temp: flash point 35 °C
• density: 0.77 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C9H22Si/c1-7(2)10(8(3)4)9(5)6/h7-10H,1-6H3
• InChI key: YDJXDYKQMRNUSA-UHFFFAOYSA-N

Description

Application

• Total synthesis of diazaquinomycins H and J using double Knorr cyclization: This paper covers the first total synthesis of diazaquinomycins, highlighting the role of triisopropylsilane in enhancing reaction efficiency (Prior & Sun, 2019).
• Reduction of cysteine‐S‐protecting groups by triisopropylsilane: An in-depth look at the chemical properties of triisopropylsilane, emphasizing its effectiveness in peptide synthesis processes (Ste. Marie & Hondal, 2018).

Analysis Note

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.765 - 0.772
Identity (IR): passes test

Safety Information

• Pictograms: GHS02
• Signal Word: Warning
• Hazard Statements: H226
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 100.4 °F - closed cup
• Flash Point(C): 38 °C - closed cup