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H20202

Sigma-Aldrich

4-Hydroxybenzophenone

98%

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About This Item

Linear Formula:
HOC6H4COC6H5
CAS Number:
Molecular Weight:
198.22
Beilstein:
777776
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

Assay

98%

mp

132-135 °C (lit.)

SMILES string

Oc1ccc(cc1)C(=O)c2ccccc2

InChI

1S/C13H10O2/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,14H

InChI key

NPFYZDNDJHZQKY-UHFFFAOYSA-N

Gene Information

rat ... Ar(24208)

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General description

4-Hydroxybenzophenone is characterized by its ability to absorb UV radiation and convert it into lower-energy radiation. This property makes it an effective photostabilizer. Its molecular structure features two aromatic rings connected by a carbonyl group, allowing for strong π-π stacking interactions, which enhance its stability and efficacy in polymer matrices. Incorporating 4-Hydroxybenzophenone into polymer matrices increases the longevity and performance of materials used in outdoor applications, such as coatings and plastics.

Application

4-Hydroxybenzophenone can be used:
  • As a photoinitiator to synthesize fluorescent triblock copolymer micelles for targeted release of cancer drugs and intracellular bioimaging. It facilitates controlled release, improving therapeutic efficacy while minimizing side effects.
  • As a photoacid catalyst for ring opening polymerization of lactones to prepare biodegradable polyesters.
  • As a precursor to synthesize functional copolymer for fabrication of nanostructured transparent metal electrodes for flexible optoelectronic devices.

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 3 - STOT RE 2

Target Organs

Liver,Kidney

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Daniel Molins-Delgado et al.
The Science of the total environment, 601-602, 975-986 (2017-06-06)
The increased use of beauty and other daily use products, in particular those containing UV filters (UV-Fs) and benzotriazoles, results in their introduction in significant amounts into the aquatic environment. In this study, we aim to assess the occurrence and
Aneesh Karkhanis et al.
Biochemical pharmacology, 146, 188-198 (2017-09-30)
Cardiac enzymes such as cytochrome P450 2J2 (CYP2J2) metabolize arachidonic acid (AA) to cardioprotective epoxyeicosatrienoic acids (EETs), which in turn are metabolized by soluble epoxide hydrolase (sEH) to dihydroxyeicosatrienoic acids (DHETs). As EETs and less potent DHETs exhibit cardioprotective and
Francesco Barsotti et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 16(4), 527-538 (2017-01-20)
The photophysics and photochemistry of 4-hydroxybenzophenone (4HOBP) are interesting because they can give some insight into the behavior of humic material. Here we show that 4HOBP has a number of fluorescence peaks: (i) an intense one at excitation/emission wavelengths Ex/Em
Benzophenone metabolism. I. Isolation of p-hydroxybenzophenone from rat urine.
A W Stocklinski et al.
Life sciences, 26(5), 365-369 (1980-02-04)
Adela Jing Li et al.
Journal of hazardous materials, 337, 115-125 (2017-05-17)
Ethyl-4-aminobenzoate (Et-PABA) is currently used as a substitute for 4-aminobenzoate (PABA) in sunscreens and anesthetic ointments. Despite its widespread use and hydrophilicity, Et-PABA has never been found in environmental waters. This study, probed the occurrence of Et-PABA in both seawater

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