922900
GPhos Pd G6 TES
Synonym(s):
GPhos OAC precatalyst TES
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About This Item
Empirical Formula (Hill Notation):
C47H70BrO4PPdSi
CAS Number:
Molecular Weight:
944.44
UNSPSC Code:
12161600
NACRES:
NA.22
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Application
GPhos Pd G6 TES is a sixth generation (G6) Buchwald palladium precatalyst for cross-coupling reactions with demonstrated use for the room temperature coupling of primary amines with aryl halides.
Learn more about G6 Buchwald precatalysts
Learn more about G6 Buchwald precatalysts
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Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Elaine C Reichert et al.
Journal of the American Chemical Society, 145(6), 3323-3329 (2023-02-01)
We report a versatile and functional-group-tolerant method for the Pd-catalyzed C-N cross-coupling of five-membered heteroaryl halides with primary and secondary amines, an important but underexplored transformation. Coupling reactions of challenging, pharmaceutically relevant heteroarenes, such as 2-H-1,3-azoles, are reported in good-to-excellent
Development of an Aryl Amination Catalyst with Broad Scope Guided by Consideration of Catalyst Stability
Scott D, et al
Journal of the American Chemical Society, 142, 15027-15037 (2020)
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