909882
Biotin-poly(ethylene glycol)-b-poly(lactide-co-glycolide)
PEG average Mn 2,000, PLGA average Mn 10,000, lactide:glycolide 50:50
Synonym(s):
Biotin-PEG-PLGA
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About This Item
Linear Formula:
H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nC16H25N6SO5
UNSPSC Code:
51171641
NACRES:
NA.25
Recommended Products
form
powder or chunks
feed ratio
lactide:glycolide 50:50
mol wt
PEG average Mn 2,000 (by NMR)
PLGA average Mn 10,000 (by NMR)
color
white to tan
storage temp.
−20°C
Application
Biotin-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The biotin functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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