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900912

Sigma-Aldrich

Biotin picolyl azide

Synonym(s):

Biotin-functionalized Picolyl Azide

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About This Item

Empirical Formula (Hill Notation):
C27H42N8O7S
Molecular Weight:
622.74
UNSPSC Code:
12352125
NACRES:
NA.22

form

powder or crystals

Quality Level

100

reaction suitability

reaction type: click chemistry

storage temp.

−20°C

Application

Biotin picolyl azide is a linker with an azide group for attachment to alkynes, a biotin for capture by streptavidin, and a picolyl group for faster azide reactivity. The picolyl azide chelates Cu(I) to enhance the reactivity of the azide-alkyne cycloaddition. This is an advantage especially when working with low concentrations of alkynes and can also enable reduction of the copper concentration.

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Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV5985
MKCV7351
MKCV1060
MKCT6646
MKCT6645

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MYC is a major oncogenic transcriptional driver of most human cancers that has remained intractable to direct targeting because much of MYC is intrinsically disordered. Here, we have performed a cysteine-reactive covalent ligand screen to identify compounds that could disrupt

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