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900863

Sigma-Aldrich

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol

≥95%

Synonym(s):

3-(3-Butyn-1-yl)-3H-diazirine-3-ethanol, Hydroxyl diazirine alkyne, Probe building block

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About This Item

Empirical Formula (Hill Notation):
C7H10N2O
CAS Number:
Molecular Weight:
138.17
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22

Quality Level

Assay

≥95%

form

liquid

density

1.08 g/mL

storage temp.

−20°C

SMILES string

OCCC1(N=N1)CCC#C

Application

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

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Product No.
Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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