765430
Gold nanoparticles
5 nm diameter, carboxylic acid functionalized, PEG 3000 coated, OD 50, dispersion in H2O
Synonym(s):
Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid
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About This Item
UNSPSC Code:
12162002
NACRES:
NA.23
Recommended Products
material
PEG 3000
Quality Level
form
dispersion in H2O
nanoparticles
packaging
poly bottle of 1 mL
OD
50
diameter
5 nm
pH
6.0-8.0 (25 °C)
solubility
water: miscible
density
1.00 g/cm3
λmax
515 nm
functional group
carboxylic acid
storage temp.
2-8°C
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General description
Carboxylic acid functionalized GNPs forms conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.
Application
Carboxylic acid functionalized, PEG 3000 coated, OD 50, and H2O dispersed gold nanoparticles (5 nm) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique. It may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique. It may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
Carboxylic acid group binds with various proteins and is used in targeted drug delivery and gene therapy.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Nóra Adányi et al.
Food chemistry, 267, 10-14 (2018-06-24)
Mycotoxins, present in a wide range of food and feed commodities, are toxic secondary metabolites produced by a number of different fungi. Certain mycotoxins do not readily degrade at high temperatures, therefore are resistant to food processing, and consequently are
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
Li Z, et al.
Journal of Medical Virology, 6, 2071-2071 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Recent advances in nanoparticle-based lateral flow immunoassay as a point-of-care diagnostic tool for infectious agents and diseases
Banerjee R and Jaiswal A
Analyst, 143(9), 1970-1996 (2018)
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