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410896

Sigma-Aldrich

2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone

98%

Synonym(s):

1-[4-(2-Hydroxyethoxy)phenyl]-2-hydroxy-2-methyl-1-propan-1-one, 2-Hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-propanone, 2-Hydroxy-2-methyl-1-[4-(2-hydroxyethoxy)phenyl]propan-1-one, 4-(2-Hydroxyethoxy)phenyl 2-hydroxy-2-propyl ketone

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About This Item

Linear Formula:
HOCH2CH2OC6H4COC(CH3)2OH
CAS Number:
106797-53-9
Molecular Weight:
224.25
MDL number:
MFCD00085267
UNSPSC Code:
12162002
PubChem Substance ID:
24865712
NACRES:
NA.23

Quality Level

200

Assay

98%

mp

88-90 °C (lit.)

SMILES string

CC(C)(O)C(=O)c1ccc(OCCO)cc1

InChI

1S/C12H16O4/c1-12(2,15)11(14)9-3-5-10(6-4-9)16-8-7-13/h3-6,13,15H,7-8H2,1-2H3

InChI key

GJKGAPPUXSSCFI-UHFFFAOYSA-N

Application

2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone can be used as a photo-initiator to synthesize:
  • Polyacrylamide-grafted chitosan nanoparticles by copolymerization of acrylamide and chitosan nanoparticles.
  • Hydrophobic polyurethane sponge through thiol–ene Click reaction.

Pictograms

Environment
GHS09

Hazard Statements

H411

Precautionary Statements

P273 - P391 - P501

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

not determined

Flash Point(C)

not determined

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jiangya Ma et al.
Carbohydrate polymers, 151, 565-575 (2016-07-31)
In the present work, a new flocculant, polyacrylamide-grafted chitosan nanoparticles (NCS-g-PAM), was synthesized by the copolymerization of acrylamide (AM) and chitosan nanoparticle (NCS) under ultraviolet irradiation using 2-hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone as photo-initiator. The NCS was prepared by the ionic gelation between chitosan
Deepak Kumar et al.
Cell transplantation, 25(12), 2213-2220 (2016-07-28)
Nucleus pulposus (NP) tissue damage can induce detrimental mechanical strain on the biomechanical performance of intervertebral discs (IVDs), causing subsequent disc degeneration. A novel, photocurable, injectable, synthetic polymer hydrogel (pHEMA-co-APMA grafted with PAA) has already demonstrated success in encapsulating and
Rami El Assal et al.
Scientific reports, 6, 39144-39144 (2016-12-23)
Cancer cells have been increasingly grown in pharmaceutical research to understand tumorigenesis and develop new therapeutic drugs. Currently, cells are typically grown using two-dimensional (2-D) cell culture approaches, where the native tumor microenvironment is difficult to recapitulate. Thus, one of
Yihu Wang et al.
Materials (Basel, Switzerland), 11(8) (2018-08-08)
Gelatin-based hydrogel, which mimics the natural dermal extracellular matrix, is a promising tissue engineering material. However, insufficient and uncontrollable mechanical and degradation properties remain the major obstacles for its application in medical bone regeneration material. Herein, we develop a facile
Xin Zhao et al.
Acta biomaterialia, 49, 66-77 (2016-11-09)
Development of natural protein-based fibrous scaffolds with tunable physical properties and biocompatibility is highly desirable to construct three-dimensional (3D), fully cellularized scaffolds for wound healing. Herein, we demonstrated a simple and effective technique to construct electrospun 3D fibrous scaffolds for
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