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120618

Sigma-Aldrich

4-Hydroxypyridine

95%

Synonym(s):

4-Pyridinol, 4-Pyridone

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About This Item

Empirical Formula (Hill Notation):
C5H5NO
CAS Number:
Molecular Weight:
95.10
Beilstein:
105800
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

95%

bp

230-235 °C/12 mmHg (lit.)

mp

150-151 °C (lit.)

SMILES string

O=C1C=CNC=C1

InChI

1S/C5H5NO/c7-5-1-3-6-4-2-5/h1-4H,(H,6,7)

InChI key

GCNTZFIIOFTKIY-UHFFFAOYSA-N

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Application

4-Hydroxypyridine was used in the synthesis of (Ag3MoO3F3) (Ag3MoO4)Cl by hydro(solvato)thermal methods. It was used as model compound to study the natural photodegradation of representative aquatic environmental contaminants.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Modelling the natural photodegradation of water contaminants: a kinetic study on the light-induced aerobic interactions between riboflavin and 4-hydroxypyridine.
Pajares A, et al.
J. Photochem. Photobiol., A, 139(2), 199-204 (2001)
H Chen et al.
Biochemistry, 32(43), 11591-11599 (1993-11-02)
We have examined the interaction of Citrobacter freundii tyrosine phenol-lyase with both L- and D-alanine. This enzyme catalyzes the racemization of alanine as a side reaction, in addition to the physiological beta-elimination of L-tyrosine to give phenol and ammonium pyruvate.
Heiko Zettl et al.
ACS chemical biology, 7(9), 1488-1495 (2012-06-26)
We present an integrated approach to identify and optimize a novel class of γ-secretase modulators (GSMs) with a unique pharmacological profile. Our strategy included (i) virtual screening through application of a recently developed protocol (PhAST), (ii) synthetic chemistry to discover
Natsuki K Kubota et al.
Bioorganic & medicinal chemistry, 11(21), 4569-4575 (2003-10-07)
Piericidins C5 (1) and C6 (2), two new members of the piericidin family, were isolated from a Streptomyces sp. and a Nocardioides sp., together with known piericidins C1 (3), C2 (4), C3 (5), C4 (6), D1 (7), and A3 (8).
Fazlul Huq et al.
Medicinal chemistry (Shariqah (United Arab Emirates)), 5(4), 372-381 (2009-08-20)
This paper describes the synthesis, characterization, cytotoxicity of a new trinuclear Pt-Pd-Pt complex code named TH8 containing two 4-hydroxypyridine ligands bound to the central metal ion. In addition to its activity against human ovarian cancer cell lines: A2780, A2780(cisR) and

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