Epoxyazadiradione Purified from the Azadirachta indica Seed Induced Mitochondrial Apoptosis and Inhibition of NFκB Nuclear Translocation in Human Cervical Cancer Cells.

Epoxyazadiradione Purified from the Azadirachta indica Seed Induced Mitochondrial Apoptosis and Inhibition of NFκB Nuclear Translocation in Human Cervical Cancer Cells.

Phytotherapy research : PTR (2017-10-19)

G Shilpa, J Renjitha, R Saranga, Francis K Sajin, Mangalam S Nair, Beena Joy, B S Sasidhar, S Priya

RESUMEN

Epoxyazadiradione (EAD) is an important limonoid present in Neem (Azadirachta indica) plant. In the present study, we have purified EAD from Neem seed and studied its anticancer potential in human cervical cancer (HeLa) cells. Cell proliferation inhibition studies indicated that the GI

MATERIALES

Referencia del producto

Marca

Descripción del producto

A8097

Sigma-Aldrich

Acridine Orange hydrochloride solution, ≥95.0% (HPLC), 10 mg/mL in H₂O

RAB0062

Sigma-Aldrich

Human CCL21 / 6ckine ELISA Kit, for serum, plasma, cell culture supernatant and urine