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Merck

A8097

Sigma-Aldrich

Acridine Orange hydrochloride solution

>95.0% purity (HPLC), solution

Sinónimos:

3,6-Bis(dimethylamino)acridine hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C17H19N3 · HCl
Número de CAS:
Peso molecular:
301.81
Beilstein:
3575587
Número MDL:
Código UNSPSC:
12171500
ID de la sustancia en PubChem:
NACRES:
NA.47

Nombre del producto

Acridine Orange hydrochloride solution, 10 mg/mL in H2O, ≥95.0% (HPLC)

Nivel de calidad

Ensayo

≥95.0% (HPLC)

Formulario

solution

concentración

10 mg/mL in H2O

técnicas

microbe id | staining: suitable

color

orange to red

εmax

47-54 at 486-492 nm in water

aplicaciones

diagnostic assay manufacturing
hematology
histology

temp. de almacenamiento

room temp

cadena SMILES

Cl[H].CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C

InChI

1S/C17H19N3.ClH/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14;/h5-11H,1-4H3;1H

Clave InChI

VSTHNGLPHBTRMB-UHFFFAOYSA-N

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Aplicación

Acridine Orange hydrochloride solution has been used to study autophagic cell death. It has also been used for the staining of chromosomes.

Acciones bioquímicas o fisiológicas

Acridine Orange is a metachromatic dye which can stain DNA, RNA and acid glycosaminoglycans. At low concentration it intercalates into DNA and precipitates RNA. However, at high concentration it denatures and precipitates both RNA and DNA. Acridine Orange is also used to analyze autophagy. It goes into acidic organelles in a pH-dependent manner. At neutral pH, acridine orange gives a green fluorescence and in acidic conditions, it accumulates in the acidic organelle giving a bright red fluorescence.

Pictogramas

Health hazard

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Muta. 2

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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