1140393

Clonidine

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: 2-(2,6-Dichloroanilino)-2-imidazoline
• Fórmula empírica (notación de Hill): C₉H₉Cl₂N₃
• Número de CAS: 4205-90-7
• Peso molecular: 230.09
• Número MDL: MFCD00055059
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: clonidine
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• cadena SMILES: Clc1c(c(ccc1)Cl)NC2=NCCN2
• InChI: 1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)
• Clave InChI: GJSURZIOUXUGAL-UHFFFAOYSA-N

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

• Pharmacological research in hypertension: Clonidine, as an alpha-2 adrenergic agonist, is widely researched for its efficacy in controlling high blood pressure, highlighting its role in cardiovascular studies and its impact on hypertension management (Luo et al., 2023).


• Neuroscience studies on ADHD: Studies utilizing clonidine in the treatment of Attention Deficit Hyperactivity Disorder (ADHD) emphasize its effectiveness as a non-stimulant option, contributing to neuroscience research by exploring its neuromodulatory effects (Goodwin et al., 2023).


• Opioid withdrawal management: Clonidine′s application in mitigating opioid withdrawal symptoms underlines its critical role in addiction medicine, providing a pharmacological approach to support recovery processes (Riccardi et al., 2023).


• Preclinical cardiovascular research: The utilization of clonidine in preclinical studies involves detailed cardiovascular assessments, helping to elucidate the drug′s mechanism in blood pressure regulation and heart rate control, crucial for developing targeted therapies (Salim et al., 2022).


• In vitro pharmacological profiling: Clonidine is extensively used in in vitro studies for pharmacological profiling, helping to determine its interaction with various neurotransmitter systems and its pharmacodynamics (Flinspach et al., 2022).

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS06
• Palabra de señalización: Danger
• Frases de peligro: H301
• Consejos de prudencia: P264 - P270 - P301 + P310 - P405 - P501
• Clasificaciones de peligro: Acute Tox. 3 Oral
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable