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Merck

1005706

USP

Ácido acético

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Ácido acético glacial

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About This Item

Fórmula lineal:
CH3CO2H
Número de CAS:
Peso molecular:
60.05
Beilstein/REAXYS Number:
506007
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor density

2.07 (vs air)

API family

glacial acetic acid

autoignition temp.

800 °F

expl. lim.

16 %, 92 °F
4 %, 59 °F

manufacturer/tradename

USP

technique(s)

gas chromatography (GC): suitable

refractive index

n20/D 1.371 (lit.)

bp

117-118 °C (lit.)

mp

16.2 °C (lit.)

density

1.04 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[F2C(F2C)13F3C]C(O)=O

InChI

1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

InChI key

QTBSBXVTEAMEQO-UHFFFAOYSA-N

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General description

Glacial acetic acid is the trivial name used to describe pure acetic acid in an anhydrous state. It is a clear and hygroscopic weak acid, typically available in concentrations ranging from 99.5% to 100%. The name "glacial" refers to the ice-like crystals that form at a temperature slightly below room temperature (16.6°C or 61.9°F), like the German term "Eisessig" (ice-vinegar). Despite being classified as a weak acid, glacial acetic acid is a corrosive poison that can cause harm or even be fatal when in contact with human tissue. Improper storage and handling of glacial acetic acid can pose inherent risks and may lead to patient injuries if not appropriately diluted. Acetic acid/acetate is a common counter ion in peptide preparations.
Glacial acetic acid USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glacial acetic acid USP reference standard for use in specified quality tests and assays. It is also used to prepare standard solution by using liquid chromatography coupled to a UV detector according to the general chapter of United States Pharmacopeia (USP). Based directly on official monographs published in the USP-NF, these highly characterized physical specimens are used in testing by pharmaceutical and related industries to help ensure the identity, strength, quality, and purity of peptide-based medicines.

Further information is available in the general chapter, 503- ACETIC ACID IN PEPTIDES, USP43-NF38 - 6741 of the USP (United States Pharmacopeia).

Other Notes

This product is part of the USP Biologics program.
Sales restrictions may apply.

Related product

Referencia del producto
Descripción
Precios

pictograms

FlameCorrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

102.2 °F - closed cup

flash_point_c

39 °C - closed cup


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Glacial Acetic Acid Adverse Events: Case Reports and Review of the Literature
Doles W, et al.
Hospital pharmacy (2015)
Acetic acid in peptides
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(5), 6741-6741 (2017)
ACETIC ACID IN PEPTIDES
USP43-NF38 - 6741:United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(5) (2017)
Ilse Cleenwerck et al.
International journal of food microbiology, 125(1), 2-14 (2008-02-02)
Acetic acid bacteria are Gram-negative, obligate aerobic bacteria that have the ability to incompletely oxidize alcohols or sugars to organic acids as end products. They are widespread in nature and most of them are capable to oxidize ethanol as substrate
Katharine Trenholme et al.
Antimicrobial agents and chemotherapy, 58(7), 3666-3678 (2014-04-16)
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