BP1234

Letrozole

British Pharmacopoeia (BP) Reference Standard

• Sinónimos: 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
• Fórmula empírica (notación de Hill): C₁₇H₁₁N₅
• Número de CAS: 112809-51-5
• Peso molecular: 285.30
• Número MDL: MFCD00866241
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• Nivel de calidad: 100
• familia API: letrozole
• Formulario: powder
• caducidad: limited shelf life, expiry date on the label
• fabricante / nombre comercial: BP
• aplicaciones: pharmaceutical; pharmaceutical small molecule
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: N#CC(C=C1)=CC=C1C(N2C=NC=N2)C3=CC=C(C#N)C=C3
• InChI: 1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
• Clave InChI: HPJKCIUCZWXJDR-UHFFFAOYSA-N
• Información sobre el gen: human ... CYP19A1(1588)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Letrozole BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Letrozole Tablets

Acciones bioquímicas o fisiológicas

Letrozole is a non-steroidal aromatase inhibitor.

Letrozole is a third generation nonsteroidal aromatase inhibitor. It is a competitive inhibitor of the aromatase enzyme system and thus inhibits the conversion of androgens to estrogens. Letrozole inhibits the aromatase enzyme by competitively binding to the heme of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues.

Envase

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Warning
• Frases de peligro: H361fd,H373
• Consejos de prudencia: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Repr. 2 - STOT RE 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable