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40458

Supelco

1-Nitrosopiperidine solution

certified reference material, 5000 μg/mL in methanol

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About This Item

Número de CAS:
100-75-4
UNSPSC Code:
41116105

grade

certified reference material
TraceCERT®

product line

TraceCERT®

CofA

current certificate can be downloaded

packaging

ampule of 1 mL

concentration

5000 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental

format

single component solution

storage temp.

2-8°C

InChI

1S/C5H10N2O/c8-6-7-4-2-1-3-5-7/h1-5H2

InChI key

UWSDONTXWQOZFN-UHFFFAOYSA-N

Categorías relacionadas

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

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Certificados de análisis (COA)

Lot/Batch Number
LRAD9118
LRAD3091
LRAC9017
LRAC6655
LRAC2459

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Kinetics of the oxidation of N-aminopiperidine with chloramine
Darwich.Ch, et al.
Kinetics and Catalysis, 50, 103-110 (2009)
Hansen L Wong et al.
Chemical research in toxicology, 16(10), 1298-1305 (2003-10-21)
N-Nitrosopiperidine (NPIP) is a potent rat nasal carcinogen whereas N-nitrosopyrrolidine (NPYR), a hepatic carcinogen, is weakly carcinogenic in the nose. NPIP and NPYR may be causative agents in human cancer. P450-catalyzed alpha-hydroxylation is the key activation pathway by which these
Kinetics of the oxidation of N-aminopiperidine with chloramine
Darwich.Ch, et al.
Kinetics and Catalysis, 50(1), 103-110 (2009)
Samuel González-Mancebo et al.
Mutation research, 558(1-2), 45-51 (2004-03-24)
The genotoxicity of nitrosopiperidine and six alkyl derivatives was studied by use of the Ames tester strains TA100 and TA1535 in the pre-incubation method. Among the compounds investigated, those exhibiting genotoxic activity under the experimental conditions employed were only genotoxic
Xiao-Yuan Xie et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 88(4), 775-782 (2010-07-24)
The aim of this study was to explore the histogenesis and carcinogenesis of pulmonary cancer induced by N-nitrosopiperidine (NPIP) in mice. NPIP is a form of N-nitrosamine found in tobacco smoke, which has been shown to be a genotoxic chemical
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