WH0004790M1

Monoclonal Anti-NFKB1 antibody produced in mouse

clone 2E6, purified immunoglobulin, buffered aqueous solution

• Sinónimos: Anti-DKFZp686C01211, Anti-EBP1, Anti-KBF1, Anti-MGC54151, Anti-NFKBp105, Anti-NFKBp50, Anti-NFkappaB, Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
• MDL number: MFCD00802846
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: mouse
• Quality Level: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 2E6, monoclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): indirect ELISA: suitable; indirect immunofluorescence: suitable; proximity ligation assay: suitable; western blot: 1-5 μg/mL
• isotype: IgG1κ
• GenBank accession no.: BC051765
• UniProt accession no.: P19838
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... NFKB1(4790)

Descripción

General description

NFKB1 (nuclear factor κB subunit 1) is a dimeric transcription factor. It belongs to the REL family. This gene is located on human chromosome 4q24.

Immunogen

NFKB1 (AAH51765, 860 a.a. ~ 969 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI

Biochem/physiol Actions

NFKB1 (nuclear factor κB subunit 1) controls the maturation of NK (natural killer) cells and effector functions. This gene helps in the upregulation of intrauterine adhesion inflammatory factors, hence NFKB1 plays a major role in inflammatory diseases.

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)