SAB5701953

Anti-Phospho-IκBα-S32 antibody produced in rabbit

• UNSPSC Code: 12352203
• NACRES: NA.43

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: human, mouse
• concentration: 0.63 mg/mL
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: P25963
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer32)
• Gene Information: human ... NFKBIA(4792)

Descripción

General description

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Immunogen

A phospho specific peptide corresponding to residues surrounding S32 of human NFKBIA.

Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable