SAB5700146

Anti-FSCN1 antibody produced in rabbit

• Sinónimos: FAN1, FSCN1, HSN, SNL, fascin, p55
• Código UNSPSC: 12352203
• NACRES: NA.43

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: 54
• reactividad de especies: mouse, rat, human
• concentración: 2.1 mg/ml
• técnicas: immunofluorescence: 1:50-1:200; immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• Nº de acceso UniProt: Q16658
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... FSCN1(6624)

Descripción

Descripción general

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin′s lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

Inmunógeno

Recombinant fusion protein containing a sequence corresponding to amino acids 394-493 of human FSCN1 (NP_003079.1).

Forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Almacenamiento y estabilidad

Store at -20℃. Avoid freeze / thaw cycles.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable