SAB4502713

Anti-SODIUM CHANNEL-PAN antibody produced in rabbit

affinity isolated antibody

• Sinónimos: CIN5, HH1, SCN5A, Sodium channel protein, cardiac muscle α-subunit
• MDL number: MFCD02097413
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 227 kDa
• species reactivity: mouse, human, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P35498
• UniProt accession no.: Q99250
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SCN2A(6323)

Descripción

General description

Anti-SODIUM CHANNEL-PAN Antibody detects endogenous levels of total SODIUM CHANNEL-PAN protein.

The SCN5A (sodium channel protein type 5 subunit α) gene is mapped to human chromosome 3p22.2. The encoded protein is known to be localized to cardiac cells.

Immunogen

The antiserum was produced against synthesized peptide derived from human Sodium Channel.

Immunogen Range: 1466-1515

Biochem/physiol Actions

SCN5A (sodium channel protein type 5 subunit α) is associated with the regulation of myocardial excitability as it conducts cardiac depolarization via inward Na⁺ current. Mutation in SCN5A causes retarded cardiac repolarization resulting in congenital long QT syndrome and also causes Brugada syndrome due to loss of gene function.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable