Saltar al contenido
Merck
Todas las fotos(1)

Documentos clave

Ver Toda la documentación

R9525

Sigma-Aldrich

RX 821002 hydrochloride

solid, ≥98% (HPLC)

Sinónimos:

2-[2-(2-Methoxy-1,4-benzodioxanyl)]imidazoline hydrochloride

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula empírica (notación de Hill):
C12H14N2O3 · HCl
Número de CAS:
109544-45-8
Peso molecular:
270.71
Número MDL:
MFCD00069343
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
24278684
NACRES:
NA.77

Nivel de calidad

100

Ensayo

≥98% (HPLC)

Formulario

solid

condiciones de almacenamiento

desiccated

color

white

solubilidad

H2O: >20 mg/mL

cadena SMILES

Cl[H].COC1(COc2ccccc2O1)C3=NCCN3

InChI

1S/C12H14N2O3.ClH/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12;/h2-5H,6-8H2,1H3,(H,13,14);1H

Clave InChI

IMPOOMVZVWKSAP-UHFFFAOYSA-N

Información sobre el gen

human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Acciones bioquímicas o fisiológicas

Selective α2-adrenoceptor antagonist

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H315,H319,H335

Clasificaciones de peligro

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

dust mask type N95 (US), Eyeshields, Gloves

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
0000395015
0000395015
027M4717V
010M4616V

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

Busque por un COA

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Thiago Roberto Lima Romero et al.
European journal of pharmacology, 608(1-3), 23-27 (2009-02-25)
Xylazine is an alpha(2)-adrenoceptor agonist extensively used in veterinary and animal experimentation. Evidence exists that alpha(2)-adrenoceptor agonists can activate opioid receptors via endogenous opioid release. Considering this idea and the multiple alpha(2) subtypes currently known (alpha(2A), alpha(2B), alpha(2C) and alpha(2D))
Axel Rominger et al.
Synapse (New York, N.Y.), 64(8), 654-657 (2010-03-26)
To test for alpha(2) adrenergic modulation of dopamine D(2/3) receptor availability in striatum of living mice using the high-affinity ligand [(18)F]fallypride and microPET. Groups of anesthetized mice were pretreated with saline, the alpha(2)-agonist clonidine (1 mg/kg), and the alpha(2)-antagonists RX821002
R L Almeida et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 301(1), R185-R192 (2011-04-09)
Lipopolysaccharide (LPS), an endotoxin from the wall of Escherichia coli, produces a general behavioral inhibition and affects several aspects of fluid-electrolyte balance. LPS inhibits thirst; however, it is not clear if it also inhibits sodium appetite. The present results show
M M Rank et al.
Journal of neurophysiology, 105(1), 410-422 (2010-11-05)
The brain stem provides most of the noradrenaline (NA) present in the spinal cord, which functions to both increase spinal motoneuron excitability and inhibit sensory afferent transmission to motoneurons (excitatory postsynaptic potentials; EPSPs). NA increases motoneuron excitability by facilitating calcium-mediated
S J Rayment et al.
British journal of pharmacology, 160(7), 1727-1740 (2010-07-24)
We have investigated the distribution of alpha-adrenoceptors in sheep internal anal sphincter (IAS), as a model for the human tissue, and evaluated various imidazoline derivatives for potential treatment of faecal incontinence. Saturation and competition binding with (3)H-prazosin and (3)H-RX821002 were
Ver todos los artículos relacionados

Artículos

α2-Adrenoceptors

Learn about alpha-2 adrenoceptor and its subtypes, mediated responses, and applications of agonists. Included is a list of available products and a comparison table.

α2-Adrenoceptors

Learn about alpha-2 adrenoceptor and its subtypes, mediated responses, and applications of agonists. Included is a list of available products and a comparison table.

α2-Adrenoceptors

Learn about alpha-2 adrenoceptor and its subtypes, mediated responses, and applications of agonists. Included is a list of available products and a comparison table.

α2-Adrenoceptors

Learn about alpha-2 adrenoceptor and its subtypes, mediated responses, and applications of agonists. Included is a list of available products and a comparison table.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico