P8374
Pyoverdines−Fe complex
from Pseudomonas fluorescens, >90% (HPLC)
Sinónimos:
Pyoverdines, Fe-Pv
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About This Item
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biological source
Pseudomonas fluorescens
Quality Level
assay
>90% (HPLC)
form
powder
solubility
H2O: ~10 mg/mL
shipped in
wet ice
storage temp.
−20°C
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Application
Pyoverdines-Fe complex has been used in cyclic voltammetry to determine potential detection windows and peak potentials.
Biochem/physiol Actions
Pyoverdines, also called pseuobactins and pyoverdins, are fluorescent siderophores that have high affinity for iron (1032 M-1), and are synthesized by fluorescent pseudomonads under iron-deficient growth conditions. Pyoverdines were shown to prevent iron toxicity produced by iron overload in hepatocyte cultures and effectively scavenges the hydroxyl and peroxyl radicals. Pyoverdines are effective in acquiring iron from transferrin and lactoferrin. Pyoverdines are also involved in the suppression of pythium-induced damping-off of tomato and promotion of growth in some higher plants.
The complex ferri-pyoverdine acts as a signaling molecule inducing the production of secreted virulence factors in Pseudomonas aeruginosa. Ferri-pyoverdines promote the growth of both P. fluorescens and P. aeruginosa in minimal medium.
Physical form
Supplied as a mixture containing mainly the succinic acid (MW=1161), 2-hydroxy glutaramide (MW=1190), and succinamide (MW=1160) forms of pyoverdines, bound to iron.
Related product
Referencia del producto
Descripción
Precios
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
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Molecular microbiology, 47(1), 195-207 (2002-12-21)
Under iron-limiting conditions, Pseudomonas aeruginosa produces a siderophore called pyoverdine. Pyoverdine is secreted into the extracellular environment where it chelates iron, and the resulting ferri-pyoverdine complexes are transported back into the bacteria by a cell surface receptor protein FpvA. Pyoverdine
Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry
Sensors (2016)
Electrochemical sensing of biomarker for diagnostics of bacteria-specific infections
Nanomedicine (London, England) (2016)
Materials (Basel, Switzerland), 12(7) (2019-04-14)
Pyoverdine is a fluorescent siderophore produced by Pseudomonas aeruginosa that can be considered as a detectable marker in nosocomial infections. The presence of pyoverdine in water can be directly linked to the presence of the P. aeruginosa, thus being a
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