P4871

Anti-Purinergic Receptor P2Y₁₂ antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• Sinónimos: Anti-ADPG-R, Anti-BDPLT8, Anti-HORK3, Anti-P2T(AC), Anti-P2Y(12)R, Anti-P2Y(AC), Anti-P2Y(ADP), Anti-P2Y(cyc), Anti-P2Y12
• Número MDL: MFCD04975335
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: lyophilized powder
• reactividad de especies: human, mouse, rat
• técnicas: immunohistochemistry: suitable using mouse brain sections; western blot: 1:200 using rat brain membranes or human platelets
• Nº de acceso UniProt: Q9H244
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... P2RY12(64805) ; mouse ... P2ry12(70839) ; rat ... P2ry12(64803)

Descripción

Descripción general

Purinergic receptor or platelet adenosine 5′-diphosphate (ADP) receptor P2Y12 is a G-protein-coupled receptor. The gene encoding it is localized on human chromosome 3q25.1.

Inmunógeno

peptide corresponding to amino acid residues 125-142 of human P2Y₁₂. This epitope is highly homologous in rat and mouse (16/18 residues identical).

Aplicación

Anti-Purinergic Receptor P2Y12 antibody produced in rabbit has been used in Western blotting.

Acciones bioquímicas o fisiológicas

Purinergic receptor or platelet adenosine 5′-diphosphate (ADP) receptor P2Y12 has a role in platelet aggregation induced by ADP. Dysfunctional mutations in the protein have been linked with bleeding disorders. Studies have indicated that mice deficient in the P2Y12 receptor show decreased tumor metastasis.

Forma física

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Frases de peligro: H412
• Consejos de prudencia: P273
• Clasificaciones de peligro: Aquatic Chronic 3
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable