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Merck

MAK107

Sigma-Aldrich

LCAT Activity Assay Kit

Supplied by Roar Biomedical, Inc.

Sinónimos:

Lecithin:cholesterol acyltransferase activity assay kit

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About This Item

Número CE:
Código UNSPSC:
12161503
NACRES:
NA.84

uso

sufficient for 100 fluorometric tests

aplicaciones

pharmaceutical

método de detección

fluorometric

enfermedades relevantes

cardiovascular diseases

temp. de almacenamiento

−20°C

Información sobre el gen

human ... LCAT(3931)

Descripción general

The plasma protein lecithin:cholesterol acyltransferase (LCAT) catalyzes the transfer of an acyl group from the sn2 position of phosphatidylcholine to the 3-hydroxyl group of cholesterol resulting in the formation cholesteryl ester. This enzymatic activity occurs on the surface of high density lipoprotein (HDL). The cholesteryl esters formed by LCAT may be packed into the core of HDL.

Aplicación

Applications for this method include high-throughput screening, mechanism of action studies and structure-activity relationship (SAR) work.
LCAT Activity Assay Kit has been used for measuring lecithin-cholesterol acyl transferase activity in plasma samples.

Características y beneficios

Compatible with high-throughput handling systems.

Idoneidad

Suitable for measuring phospholipase activity of LCAT in plasma or serum.

Principio

The LCAT Activity Assay Kit is a fluorometric assay useful for measuring phospholipase activity of (λEx=390 nm/λEm=470 nm) LCAT. The assay may be validated by inhibition of LCAT with iodoacetate or another spectrally benign (not Ellman′s reagent) LCAT inhibitor.

Solo componentes del kit

Referencia del producto
Descripción

  • Substrate Reagent .1 mL

  • READ Reagent 30 mL

  • LCAT Assay Buffer 20 mL

Producto relacionado

Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Código de clase de almacenamiento

3 - Flammable liquids

Punto de inflamabilidad (°F)

49.5 °F

Punto de inflamabilidad (°C)

9.7 °C


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