G8255
Glutamic-Pyruvic Transaminase from porcine heart
lyophilized powder, ≥75 units/mg protein
Sinónimos:
L-Alanine: 2-Oxoglutarate Aminotransferase, Alanine Aminotransferase (catalytic concentration), GPT
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About This Item
Productos recomendados
origen biológico
Porcine heart
Nivel de calidad
Formulario
lyophilized powder
actividad específica
≥75 units/mg protein
composición
Protein, 75-95%
técnicas
cell culture | mammalian: suitable
color
light yellow to yellow
actividad extraña
L-glutamic dehydrogenase, lactic dehydrogenase and malic dehydrogenase ≤0.01%
glutamic-oxalacetic transaminase ≤0.1%
temp. de almacenamiento
−20°C
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Descripción general
Glutamic-pyruvic transaminase (GPT) is localized majorly in the liver.
Research area: Cell Signaling
Research area: Cell Signaling
Aplicación
Glutamic-Pyruvic Transaminase from porcine heart has been used:
- in the transamination assay with a racemic mixture of synthetic 3-methyl-2-oxoglutarate
- to remove glutamate from the cell culture medium used for culturing human embryonic kidney (HEK293) cells
- in the lactate-dehydrogenase (LD)-coupled alanine transaminase (ALT) reaction kinetic studies
Acciones bioquímicas o fisiológicas
Glutamic-pyruvic transaminase (GPT) mediates the transfer of the amino group to α-ketoglutarate from l-alanine which results in pyruvate and glutamate.Thereby GPT plays a key role in gluconeogenesis and amino acid metabolism. The role of GPT in various kinds of tumors has been reported.
Glutamic-pyruvic transaminase (GPT) is located in most cells in the body, but is found in highest concentrations in the liver. It is used as a marker of liver disease due to the release of GPT into the blood following liver cell necrosis.
Definición de unidad
One unit will convert 1.0 μmole of α-ketoglutarate to L-glutamate per min at pH 7.6 at 37 °C in the presence of L-alanine.
Forma física
Lyophilized powder containing citrate and acetate
Almacenamiento y estabilidad
Tightly closed. Dry. Keep locked up or in an area accessible only to qualified or authorized
persons
persons
Nota de análisis
Protein determined by biuret
Producto relacionado
Palabra de señalización
Danger
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Resp. Sens. 1
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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