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F9926

Sigma-Aldrich

FIM-1

≥99% purity (TLC), powder

Sinónimos:

N-[3-(3-[2,5-Dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl)propyl]-3′,6′-dihydroxy-3-oxospiro[isobenzofuran-1[3H],9′-[9H]xanthene]-5-carboxamide

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About This Item

Fórmula empírica (notación de Hill):
C45H31N4O8
Número de CAS:
220518-50-3
Peso molecular:
755.75
MDL number:
MFCD03453075
UNSPSC Code:
12171500
PubChem Substance ID:
329799791
NACRES:
NA.47

product name

FIM-1,

assay

≥99% (TLC)

Quality Level

200

form

powder

color

red

solubility

DMSO or DMF: soluble

εmax

81.8 at 486 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

shipped in

dry ice

storage temp.

−20°C

SMILES string

Cn1c(cc2ccccc12)C3=C(C(=O)NC3=O)c4cn(CCCNC(=O)c5ccc6c(c5)C(=O)OC67c8ccc(O)cc8Oc9cc(O)ccc79)c%10ccccc4%10

InChI

1S/C45H32N4O8/c1-48-34-9-4-2-7-24(34)20-36(48)40-39(42(53)47-43(40)54)30-23-49(35-10-5-3-8-28(30)35)18-6-17-46-41(52)25-11-14-31-29(19-25)44(55)57-45(31)32-15-12-26(50)21-37(32)56-38-22-27(51)13-16-33(38)45/h2-5,7-16,19-23,50-51H,6,17-18H2,1H3,(H,46,52)(H,47,53,54)

InChI key

WZJAWTNAOLZZOO-UHFFFAOYSA-N

Categorías relacionadas

Biochem/physiol Actions

A fluorescent conjugate of bisindolylmaleimide that specifically binds phosphokinase C at the active site. Can monitor enzyme activation and translocation. This reagent is not membrane permeable. The diacetate form (Sigma No. F9801) is membrane permeable.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Computationally understanding the molecular mechanisms that give rise to cell signaling responses upon different environmental, chemical, and genetic perturbations is a long-standing challenge that requires models that fit and predict quantitative responses for new biological conditions. Overcoming this challenge depends

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