F1308

Fosinopril sodium

≥98% (HPLC), powder

• Sinónimos: (2S,4S)-4-Cyclohexyl-1-(2-{[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylic acid, Acecor, Eosinopril, Fosinopril, Monopril, SQ 28555, Secorvas, Staril
• Fórmula empírica (notación de Hill): C₃₀H₄₅NO₇P · Na
• Número de CAS: 88889-14-9
• Peso molecular: 585.64
• Número MDL: MFCD23704184
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329799677
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• condiciones de almacenamiento: desiccated
• color: white to off-white
• solubilidad: H₂O: >20 mg/mL
• emisor: Bristol-Myers Squibb
• temp. de almacenamiento: −20°C
• cadena SMILES: O=C([O-])[C@H]1N(C(CP(CCCCC2=CC=CC=C2)(O[C@@H](C(C)C)OC(CC)=O)=O)=O)C[C@H](C3CCCCC3)C1.[Na+]
• InChI: 1S/C30H46NO7P.Na/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24;/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35);/q;+1/p-1/t25-,26+,30+,39?;/m1./s1
• Clave InChI: TVTJZMHAIQQZTL-TXDYNIFHSA-M

Descripción

Descripción general

Fosinopril lowers blood pressure and functions as an antihypertensive agent. It is an ester prodrug. Fosinopril is metabolised by the liver and excreted from the body by liver and kidney. It is used to treat heart failure.

Acciones bioquímicas o fisiológicas

Fosinopril is an angiotensin converting enzyme (ACE) inhibitor.

Fosinopril is an angiotensin converting enzyme (ACE) inhibitor. Fosinopril is also known to inhibit the activity of the peptide transporter PEPT2.

Características y beneficios

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de señalización: Warning
• Frases de peligro: H319,H361d
• Consejos de prudencia: P202 - P264 - P280 - P305 + P351 + P338 - P308 + P313 - P337 + P313
• Clasificaciones de peligro: Eye Irrit. 2 - Repr. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable