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Merck

C4654

Sigma-Aldrich

Cytidine

BioReagent, suitable for cell culture, powder, ≥99%

Sinónimos:

Cytosine β-D-riboside, Cytosine-1-β-D-ribofuranoside

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About This Item

Fórmula empírica (notación de Hill):
C9H13N3O5
Número de CAS:
Peso molecular:
243.22
Beilstein:
89173
Número CE:
Número MDL:
Código UNSPSC:
12352207
ID de la sustancia en PubChem:
NACRES:
NA.75
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origen biológico

synthetic

Nivel de calidad

Línea del producto

BioReagent

Ensayo

≥99%

Formulario

powder

técnicas

cell culture | mammalian: suitable

mp

210-220 °C (dec.) (lit.)

solubilidad

H2O: 50 mg/mL

cadena SMILES

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O

InChI

1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1

Clave InChI

UHDGCWIWMRVCDJ-XVFCMESISA-N

Información sobre el gen

mouse ... Uck1(22245)

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Descripción general

Cytidine is a nucleoside molecule. It is formed when cytosine is attached to a ribose ring through a β-N1-glycosidic bond.[1]

Aplicación

Cytidine has been used as a component to prepare ribonucleoside stock solution to assess its effects on the anaerobic growth of several Bacillus mojavensis strains.[2]
Cytidine has been used as a non-essential aminoacid component of minimal essential medium (MEM) to analyse interspecies somatic cell nucleus transfer (iSCNT)-derived blastocysts.[3] It has also been used as a supplement in the culture medium of HeLa cells, to study the effects of cytidine addition on rods and rings (RR) induced by glutamine deprivation.[4]

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Visite la Librería de documentos

Filippo M Cernilogar et al.
Nucleic acids research, 47(17), 9069-9086 (2019-07-28)
Pioneer transcription factors (PTF) can recognize their binding sites on nucleosomal DNA and trigger chromatin opening for recruitment of other non-pioneer transcription factors. However, critical properties of PTFs are still poorly understood, such as how these transcription factors selectively recognize
G P Gerrits et al.
Clinical chemistry, 34(7), 1439-1442 (1988-07-01)
Disturbances in the metabolism of purines and pyrimidines in neurologically affected patients can be reflected by aberrant concentrations of nucleosides and nucleobases in cerebrospinal fluid (CSF). However, normal values, especially for children at different ages, are lacking. We collected 1000
Beata Brozek-Pluska et al.
International journal of molecular sciences, 20(14) (2019-07-13)
Noninvasive Raman imaging of non-fixed and unstained human colon tissues based on vibrational properties of noncancerous and cancerous samples can effectively enable the differentiation between noncancerous and tumor tissues. This work aimed to evaluate the biochemical characteristics of colon cancer
Leonidas Chouliaras et al.
Neurobiology of aging, 34(9), 2091-2099 (2013-04-16)
Epigenetic dysregulation of gene expression is thought to be critically involved in the pathophysiology of Alzheimer's disease (AD). Recent studies indicate that DNA methylation and DNA hydroxymethylation are 2 important epigenetic mechanisms that regulate gene expression in the aging brain.
Diana Guallar et al.
Nature genetics, 50(3), 443-451 (2018-02-28)
Ten-eleven translocation (TET) proteins play key roles in the regulation of DNA-methylation status by oxidizing 5-methylcytosine (5mC) to generate 5-hydroxymethylcytosine (5hmC), which can both serve as a stable epigenetic mark and participate in active demethylation. Unlike the other members of

Questions

1–3 of 3 Questions  
  1. How do I dissolve Product No. C4654, Cytidine?

    1 answer
    1. The product is tested for solubility in water at 50 mg/mL.  It may be soluble at higher concentrations as well.  Solutions of cytidine are clear or can be faint yellow in color.

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  2. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

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  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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