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Key Documents

AV39110

Sigma-Aldrich

Anti-CXXC1 antibody produced in rabbit

IgG fraction of antiserum

Sinónimos:

Anti-2410002I16Rik, Anti-5830420C16Rik, Anti-CGBP, Anti-CXXC finger 1 (PHD domain), Anti-HsT2645, Anti-PCCX1, Anti-PHF18, Anti-hCGBP

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

76 kDa

species reactivity

guinea pig, dog, horse, rabbit, mouse, rat, human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CXXC1(30827)

Immunogen

Synthetic peptide directed towards the C terminal region of human CXXC1

Biochem/physiol Actions

CXXC1 (CXXC finger protein 1) is a component of euchromatic Setd1A histone H3K4 methyltransferase complex. It regulates histone and cytosine methylation which in turn mediates cellular differentiation and development in vertebrates.

Sequence

Synthetic peptide located within the following region: RVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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Courtney M Tate et al.
The FEBS journal, 277(1), 210-223 (2009-12-03)
CXXC finger protein 1 (Cfp1), encoded by the CXXC1 gene, is a component of the euchromatic Setd1A histone H3K4 methyltransferase complex, and is a critical regulator of histone methylation, cytosine methylation, cellular differentiation, and vertebrate development. Murine embryonic stem (ES)

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