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Key Documents

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A9272

Sigma-Aldrich

Adenosine 3′-monophosphate

from yeast

Sinónimos:

3′-AMP, 3′-Adenylic acid

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About This Item

Fórmula empírica (notación de Hill):
C10H14N5O7P
Número de CAS:
84-21-9
Peso molecular:
347.22
Beilstein/REAXYS Number:
54478
EC Number:
201-521-8
MDL number:
MFCD00005746
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
24891429
NACRES:
NA.51

biological source

yeast

assay

≥98% (HPLC)

form

powder

solubility

1 N NH4OH: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H]3O

InChI

1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

InChI key

LNQVTSROQXJCDD-KQYNXXCUSA-N

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Application

Adenosine 3′-monophosphate (3′-AMP) is a metabolite produced from hydrolysis of 2′,3′-cAMP by a family of metal-dependent phosphodiesterases. 3′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′,3′-cAMP and 3′-AMP represent a new unexplored pathway for adenosine-based cell regulation.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 214, 28-35 (2018-09-04)
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1011, 171-178 (2016-01-17)
Detoxification of lithocholic acid (LCA) to lithocholic acid sulfate (LCA-S) is catalyzed by sulfotransferases, mainly SULT2A1. We developed and validated an ultra-high performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) method to quantify human liver cytosolic-dependent LCA sulfation. Chromatographic separation was achieved
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