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A9186

Sigma-Aldrich

Alcian Blue 8GX

BioReagent, suitable for detection of glycoproteins

Sinónimos:

Alcian Blue, Ingrain Blue 1

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About This Item

Fórmula empírica (notación de Hill):
C56H68Cl4CuN16S4
Número de CAS:
33864-99-2
Peso molecular:
1298.86
Colour Index Number:
74240
EC Number:
251-705-7
MDL number:
MFCD00010720
UNSPSC Code:
12171500
PubChem Substance ID:
24891421
NACRES:
NA.32

product line

BioReagent

Quality Level

100

form

powder

composition

Dye content, ~50%

technique(s)

electrophoresis: suitable

suitability

suitable for detection of glycoproteins

SMILES string

[Cl-].[Cl-].[Cl-].[Cl-].CN(C)C(\SCc1ccc2c3nc(nc4n5[Cu]n6c(nc7nc(nc5c8cc(CS\C(N(C)C)=[N+](\C)C)ccc48)c9ccc(CS\C(N(C)C)=[N+](\C)C)cc79)c%10ccc(CS\C(N(C)C)=[N+](\C)C)cc%10c6n3)c2c1)=[N+](/C)C

InChI

1S/C56H68N16S4.4ClH.Cu/c1-65(2)53(66(3)4)73-29-33-17-21-37-41(25-33)49-57-45(37)62-50-43-27-35(31-75-55(69(9)10)70(11)12)19-23-39(43)47(59-50)64-52-44-28-36(32-76-56(71(13)14)72(15)16)20-24-40(44)48(60-52)63-51-42-26-34(18-22-38(42)46(58-51)61-49)30-74-54(67(5)6)68(7)8;;;;;/h17-28H,29-32H2,1-16H3;4*1H;/q+2;;;;;+2/p-4

InChI key

CKLBXIYTBHXJEH-UHFFFAOYSA-J

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General description

Alcian Blue 8GX is a cationic phthalocyanine dye. It has an ability to interact with sulphated glycosaminoglycan. It is used as a counterstain to visualize histological tissue sections. In addition, alcian blue 8GX also aids in the in-situ quantification of marine biofilms produced by marine bacteria.

Application

Alcian Blue 8GX has been used:
  • for the quantification of sulphated glycosaminoglycan
  • to stain differentiated chondrocytes to access proteoglycan′s synthesis by these cells
  • to stain Multi-lineage differentiation of hemangioma-derived perivascular cells (Hem-PCs)
  • in histological staining to detect neutral and charged carbohydrate residues

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
SHBS1830
SHBQ9242
SHBP4331
MKCJ3543
MKCH2605

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Anca Florentina Caliman et al.
Journal of hazardous materials, 144(1-2), 265-273 (2006-11-23)
The photocatalytic degradation of Alcian Blue 8 GX, a cationic copper phthalocyanine dye, has been investigated in aqueous suspensions containing the commercial catalyst TiO(2) P-25. The photodegradation of the organic molecule follows approximately a pseudo-first kinetic order, according to the
Chloe Moreau et al.
Current biology : CB, 29(1), 35-50 (2018-12-18)
Limb position along the body is highly consistent within one species but very variable among vertebrates. Despite major advances in our understanding of limb patterning in three dimensions, how limbs reproducibly form along the antero-posterior axis remains largely unknown. Hox
Inga Katharina Fuhrmann et al.
Acta histochemica, 117(3), 243-254 (2015-04-02)
The purpose of our study was to analyze the distribution of the major extracellular matrix glycosaminoglycan hyaluronan (HA), its receptor CD44 and cells which influence (re)modeling of the extracellular matrix (T- and B-cells, macrophages, endothelial cells) in menisci obtained from
A R Ribeiro et al.
Biointerphases, 7(1-4), 38-38 (2012-06-16)
Mutable collagenous tissues (MCTs) of echinoderms can be regarded as intelligent and dynamic biomaterials, due to their ability to reversibly change their mechanical properties in a short physiological time span. This mutability phenomenon is nervously mediated and involves secreted factors
J M Campos et al.
Regenerative biomaterials, 6(1), 49-59 (2019-02-12)
Development of synthetic bone substitutes has arisen as a major research interest in the need to find an alternative to autologous bone grafts. Using an ovine model, the present pre-clinical study presents a synthetic bone graft (Bonelike®) in combination with
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