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344M-9

Sigma-Aldrich

Tyrosinase (T311) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

T311, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (344M-94)
vial of 0.5 mL concentrate (344M-95)
bottle of 1.0 mL predilute (344M-97)
vial of 1.0 mL concentrate (344M-96)
bottle of 7.0 mL predilute (344M-98)

fabricante / nombre comercial

Cell Marque®

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotipo

IgG2a

control

melanoma

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic

Información sobre el gen

human ... TYR(7299)

Descripción general

Tyrosinase is an enzyme, amongst a family of enzymes, which is involved in the biosynthesis of melanin. Anti-tyrosinase has been found to be quite specific for melanotic lesions such as malignant melanoma and melanotic neurofibroma. Essentially no carcinomas express this marker.

Calidad


IVD

IVD

IVD

RUO

Ligadura / enlace

Tyrosinase Positive Control Slides, Product No. 344S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: [email protected]

Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Jean Kanitakis et al.
The American Journal of dermatopathology, 24(6), 498-501 (2002-11-28)
Trichoblastomas (TBs) are benign skin tumors recapitulating the differentiation of hair follicles. Several pathologic variants have been described, including the rare pigmented TB. We report a deeply pigmented nodular tumor excised on the scalp of a 32-year-old African woman, which
Grant E Eudy et al.
Human pathology, 34(8), 797-802 (2003-09-25)
Sentinel lymph node (SLN) biopsy is performed on patients with malignant melanoma (MM) to assess the need for selective complete lymphadenectomy. Melanoma metastasis to regional lymph nodes is an important prognostic indicator in patients with MM. This study assesses the
Nele Jaanson et al.
Melanoma research, 13(5), 473-482 (2003-09-27)
Tyrosinase, the critical enzyme in melanin synthesis, is also found to be expressed in most malignant melanomas and can serve as a target for the immune response by both CD4+ and CD8+ T-cells. Therefore it could be used as a
K J Busam et al.
The American Journal of dermatopathology, 22(3), 237-241 (2000-06-28)
Histiocytic tumors can be confused with melanocytic nevi and malignant melanoma and vice versa. To explore the use of immunohistochemistry for this diagnostic problem, we examined the expression of S-100 protein, gp100 (the antigen recognized by HMB-45), tyrosinase (T311), Melan-A
C B Meije et al.
The Journal of pathology, 190(5), 572-578 (2000-03-23)
The in situ expression of antigens associated with melanosomes (gp-100), pigmentation (PAA), tyrosinase (TRP-1), melanoma (MAA-1/MAA-2), and HLA-DR was investigated immunohistochemically in frozen archival specimens of common acquired melanocytic naevi, in dysplastic melanocytic naevi, and in lymph node metastases of

Artículos

IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.

IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.

IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.

IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.

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