241R-1

Cyclin D1 (SP4) Rabbit Monoclonal Antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: culture supernatant
• tipo de anticuerpo: primary antibodies
• clon: SP4, monoclonal
• descripción: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formulario: buffered aqueous solution
• reactividad de especies: human
• envase: vial of 0.1 mL concentrate (241R-14); vial of 0.5 mL concentrate (241R-15); bottle of 1 mL predilute (241R-17); vial of 1 mL concentrate (241R-16); bottle of 7 mL predilute (241R-18)
• fabricante / nombre comercial: Cell Marque^®
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
• dilution: 1:100-1:500
• isotipo: IgG
• control: mantle cell lymphoma
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• visualización: nuclear
• Información sobre el gen: human ... CCND1(595)

Descripción

Descripción general

Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. Cyclins are proteins that govern transitions through distinct phases of the cell cycle by regulating the activity of the cyclin-dependent kinases. In mid-to-late G1 phase of the cell cycle, cyclin D1 shows a maximum expression following growth factor stimulation. Anti-cyclin D1 has been successfully employed and is a promising tool for further studies in both cell cycle biology and cancer associated abnormalities. This antibody is useful for separating mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Hairy cell leukemia and plasma cell myeloma can weakly express Cyclin D1.

Calidad

IVD

IVD

IVD

RUO

Ligadura / enlace

Cyclin D1 Positive Control Slides, Product No. 241S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: [email protected]

Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable