223A-1

A-1-Antitrypsin Rabbit Polyclonal Antibody

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100; 500
• conjugado: unconjugated
• forma del anticuerpo: Ig fraction of antiserum
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• descripción: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formulario: buffered aqueous solution
• reactividad de especies: human
• envase: vial of 0.1 mL concentrate (223A-14); vial of 0.5 mL concentrate (223A-15); bottle of 1.0 mL predilute (223A-17); vial of 1.0 mL concentrate (223A-16); bottle of 7.0 mL predilute (223A-18)
• fabricante / nombre comercial: Cell Marque^®
• técnicas: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:2000
• control: tonsil
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• visualización: cytoplasmic

Descripción

Descripción general

Alpha-1-Antitrypsin is a protease inhibitor from the serpin superfamily, which inhibits a number of protease enzymes from inflammatory cells. It is an acute-phase plasma protein predominantly produced in hepatocytes, although it is also made in enterocytes and some mononuclear white blood cells. Alpha-1-antitrypsin immunohistochemistry is used to detect the accumulation of alpha-1-antitrypsin in hepatic lesions and histiocytic tumors.
The immunohistochemical staining of Alpha-1-Antitrypsin is considered to be very useful in the study of inherited AAT deficiency, benign and malignant hepatic tumors, and yolk sac carcinomas. Positive staining for A-1-Antitrypsin may also be used in the detection of benign and malignant lesions of a histiocytic nature. The sensitivity and specificity of the results have made this antibody a useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with portal fibrosis of uncertain etiology.

Calidad

IVD

IVD

IVD

RUO

Ligadura / enlace

A-1-Antitrypsin Positive Control Slides , Product No. 223S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

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Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany