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143M-1

Sigma-Aldrich

CD43 (MT1) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

MT1, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (143M-14)
vial of 0.5 mL concentrate (143M-15)
bottle of 1.0 mL predilute (143M-17)
vial of 1.0 mL concentrate (143M-16)
bottle of 7.0 mL predilute (143M-18)

fabricante / nombre comercial

Cell Marque®

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotipo

IgG1

control

tonsil

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

membranous

Información sobre el gen

human ... SPN(6693)

Descripción general

From 70 to 90% of T-cell Lymphomas and from 22 to 37% of B cell Lymphomas are labeled with this antibody. No reactivity has been observed with reactive B cells. So, a B lineage population that co-expresses a T-cell marker is highly likely to be a malignant lymphoma rather than a reactive B cell population. When used in combination with CD45 and L26, effective immunophenotyping of the majority of paraffin-embedded lymphomas can be obtained. Co-staining of a lymphoid infiltrate with CD20 and CD3 argues against a reactive process and favors lymphoma.

Calidad


IVD

IVD

IVD

RUO

Ligadura / enlace

CD43 Positive Control Slides, Product No. 143S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: [email protected]

Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Visite la Librería de documentos

Arber, DA, et al.
Appl. Immunohistochem., 1, 88-96 (1993)
J K Chan et al.
Histopathology, 12(5), 461-480 (1988-05-01)
This review aims to provide a simple guide and quick reference to the terminology and diagnostic applications of leucocyte monoclonal antibodies. The differentiation cluster terminology, where applicable, is used throughout.
J G Strickler et al.
Human pathology, 18(8), 808-814 (1987-08-01)
The immunoreactivity of eight monoclonal antibodies was evaluated on 45 routinely processed lymphomas (22 T-cell lymphomas, 11 B-cell lymphomas, and 12 cases of Hodgkin's disease). Two antibodies reactive with leukocyte common (T200) antigens (PD7/26 and 2B11) stained most of the
K Sheibani et al.
Human pathology, 18(10), 1051-1062 (1987-10-01)
From the study of over 3,000 immunologically well characterized cases, we have developed a systematic approach for the immunohistologic evaluation of lymphoproliferative disorders (LPD). By using a basic screening panel of antibodies on fresh-frozen sections, LPD can be reliably immunophenotyped.
J M Cabeçadas et al.
Histopathology, 19(5), 419-424 (1991-11-01)
Five antibodies, MT1 (CD43), UCHL1 (CD45RO), OPD4, poly-CD3 and beta F1, were assessed for their reactivity with 50 archival cases of T-cell lymphoma in formalin-fixed paraffin-embedded tissue. All cases had been previously characterized as T-cell lymphomas, and the histological types

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