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Key Documents

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159417

Sigma-Aldrich

Hydroxylamine hydrochloride

ReagentPlus®, 99%

Sinónimos:

Hydroxylammonium chloride

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About This Item

Fórmula lineal:
NH2OH · HCl
Número de CAS:
5470-11-1
Peso molecular:
69.49
Beilstein/REAXYS Number:
3539763
EC Number:
226-798-2
MDL number:
MFCD00051089
UNSPSC Code:
12352300
PubChem Substance ID:
329751008
NACRES:
NA.21

vapor pressure

0.001 hPa ( 50 °C)

Quality Level

100

product line

ReagentPlus®

assay

99%

form

crystalline

technique(s)

inhibition assay: suitable

pH

2.5-3.5 (20 °C, 50 g/L)

mp

155-157 °C (dec.) (lit.)

density

1.67 g/mL at 25 °C (lit.)

SMILES string

Cl.NO

InChI

1S/ClH.H3NO/c;1-2/h1H;2H,1H2

InChI key

WTDHULULXKLSOZ-UHFFFAOYSA-N

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General description

Hydroxylamine hydrochloride (Hydroxylammonium chloride) participates in the synthesis of 1,2,4-oxadiazoles, secondary amides and tertiary amides.
Hydroxylamine hydrochloride (NH2OH.HCl) is a hygroscopic salt widely used as a reactant in electrophilic substitution reactions, oxidation, and reduction reactions. It is also used in the synthesis of nitriles, pyrazoles, isoxazoles, nitrones, and pyridine.

Application

Hydroxylamine hydrochloride can be used as a reactant:
  • in the synthesis of primary amides from aldehydes in the presence of cesium carbonate (Cs2CO3) as a catalyst.
  • in the conversion of alicyclic /aliphatic carbonyl compounds and the aromatic aldehydes into corresponding oximes.
  • in the one-pot synthesis of nitriles from aldehydes in the presence of sodium sulfate (anhyd) and sodium bicarbonate catalysts.
  • It can also be used as a reducing agent in the preparation of single-layer reduced graphene oxide (RGO) sheets and films.

Biochem/physiol Actions

Inhibidor MAO; inhibe la agregación de plaquetas.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

target_organs

spleen

Storage Class

4.1A - Other explosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Magnesia-supported hydroxylamine hydrochloride in the presence of sodium carbonate as an efficient reagent for the synthesis of 1, 2, 4-oxadiazoles from nitriles.
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