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Y0000878

Atropine

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Hyoscyamine, Tropine tropate, endo-(±)-α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester

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About This Item

Fórmula empírica (notación de Hill):
C17H23NO3
Número de CAS:
51-55-8
Peso molecular:
289.37
Beilstein:
91260
Número MDL:
MFCD00022622
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329831200
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

atropine

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3

InChI

1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?

Clave InChI

RKUNBYITZUJHSG-SPUOUPEWSA-N

Información sobre el gen

human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Atropine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Acciones bioquímicas o fisiológicas

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

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Atropine sulfate, United States Pharmacopeia (USP) Reference Standard

A1400000

Atropine sulfate, European Pharmacopoeia (EP) Reference Standard

M1300000

Methylatropine bromide, European Pharmacopoeia (EP) Reference Standard

Y0000845

Atropine for peak identification, European Pharmacopoeia (EP) Reference Standard

Y0000816

Atropine impurity B, European Pharmacopoeia (EP) Reference Standard

PHR1379

Atropine Sulfate, Pharmaceutical Secondary Standard; Certified Reference Material

BP023

Atropine sulfate, British Pharmacopoeia (BP) Reference Standard

BP036

Benzatropine mesilate, British Pharmacopoeia (BP) Reference Standard

1044990

Atropine, United States Pharmacopeia (USP) Reference Standard

BP689

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Pictogramas

Skull and crossbones
GHS06

Palabra de señalización

Danger

Frases de peligro

H300 + H330

Clasificaciones de peligro

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Código de clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Baptiste Berton et al.
Pharmaceutics, 12(8) (2020-08-23)
Myopia is an ophthalmic condition affecting more than 1/5th of the world population, especially children. Low-dose atropine eyedrops have been shown to limit myopia evolution during treatment. However, there are currently no commercial industrial forms available and there is little
Joanna Kur et al.
The Journal of physiology, 592(3), 491-504 (2013-11-28)
Purinergic control of vascular tone in the CNS has been largely unexplored. This study examines the contribution of endogenous extracellular ATP, acting on vascular smooth muscle cells, in controlling vascular tone in the in vivo rat retina. Retinal vessels were
M M McCarron et al.
Pediatrics, 87(5), 694-700 (1991-05-01)
Eight pediatric accidental overdoses of diphenoxylate-atropine (Lomotil) are reported, and 28 literature cases are reviewed. This overdose is primarily an opioid intoxication, occasionally associated with atropine toxicity. Only 6 of 36 children showed signs of atropine overdose (central nervous system
Yossi Rosman et al.
Annals of internal medicine, 160(9), 644-648 (2014-05-07)
On the night of 21 August 2013, sarin was dispersed in the eastern outskirts of Damascus, killing 1400 civilians and severely affecting thousands more. This article aims to delineate the clinical presentation and management of a mass casualty event caused
Ariane Rossi et al.
Anesthesia and analgesia, 119(4), 947-955 (2014-08-05)
Cerebral cholinergic transmission plays a key role in cognitive function, and anticholinergic drugs administered during the perioperative phase are a hypothetical cause of postoperative cognitive dysfunction (POCD). We hypothesized that a perioperative increase in serum anticholinergic activity (SAA) is associated
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