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Y0000676

Gemcitabine impurity A

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Cytosine, 4-Amino-2-hydroxypyrimidine, 4-Aminopyrimidin-2-(1H)-one

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About This Item

Fórmula empírica (notación de Hill):
C4H5N3O
Número de CAS:
71-30-7
Peso molecular:
111.10
Beilstein:
2637
Número MDL:
MFCD00006034
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329831090
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

gemcitabine

fabricante / nombre comercial

EDQM

mp

>300 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

NC1=NC(=O)NC=C1

InChI

1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)

Clave InChI

OPTASPLRGRRNAP-UHFFFAOYSA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Gemcitabine impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Lot/Batch Number

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Saki Kondo et al.
PloS one, 9(9), e108627-e108627 (2014-10-03)
Non-coding small RNAs are involved in many physiological responses including viral life cycles. Adenovirus-encoding small RNAs, known as virus-associated RNAs (VA RNAs), are transcribed throughout the replication process in the host cells, and their transcript levels depend on the copy
Rebecca C Richmond et al.
Human molecular genetics, 24(8), 2201-2217 (2015-01-02)
Maternal smoking during pregnancy has been found to influence newborn DNA methylation in genes involved in fundamental developmental processes. It is pertinent to understand the degree to which the offspring methylome is sensitive to the intensity and duration of prenatal
Gitali Devi et al.
Nucleic acids research, 42(6), 4008-4018 (2014-01-16)
Peptide nucleic acids (PNAs) have been developed for applications in biotechnology and therapeutics. There is great potential in the development of chemically modified PNAs or other triplex-forming ligands that selectively bind to RNA duplexes, but not single-stranded regions, at near-physiological
C P Walsh et al.
Current topics in microbiology and immunology, 301, 283-315 (2006-03-31)
Cytosine methylation is a common form of post-replicative DNA modification seen in both bacteria and eukaryotes. Modified cytosines have long been known to act as hotspots for mutations due to the high rate of spontaneous deamination of this base to
Benjamin Delatte et al.
Briefings in functional genomics, 12(3), 191-204 (2013-04-30)
Epigenetic genome marking and chromatin regulation are central to establishing tissue-specific gene expression programs, and hence to several biological processes. Until recently, the only known epigenetic mark on DNA in mammals was 5-methylcytosine, established and propagated by DNA methyltransferases and
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