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Documentos clave

P2120000

Piretanide

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

4-Phenoxy-3-(1-pyrrolidinyl)-5-sulfamoylbenzoic acid

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About This Item

Fórmula empírica (notación de Hill):
C17H18N2O5S
Número de CAS:
Peso molecular:
362.40
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

piretanide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C17H18N2O5S/c18-25(22,23)15-11-12(17(20)21)10-14(19-8-4-5-9-19)16(15)24-13-6-2-1-3-7-13/h1-3,6-7,10-11H,4-5,8-9H2,(H,20,21)(H2,18,22,23)

InChI key

UJEWTUDSLQGTOA-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Piretanide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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V Homuth et al.
The American journal of cardiology, 72(9), 666-671 (1993-09-15)
To test the dose responses of piretanide, ramipril, and their combination in patients with essential hypertension, a prospective, randomized, double-blind, placebo-controlled trial was conducted in 480 patients. Twelve separate groups were studied: placebo, piretanide 3 mg, piretanide 6 mg, ramipril
N Takamura et al.
Pharmaceutical research, 13(7), 1015-1019 (1996-07-01)
The purpose of this study was to investigate the binding mechanism of loop diuretics with HSA and to characterize the binding site on HSA. Quantitative analysis of potential interaction between ligands bound to HSA was performed by equilibrium dialysis and
G Ruf et al.
European journal of clinical pharmacology, 46(6), 545-550 (1994-01-01)
The pharmacokinetics and pharmacodynamics of single oral doses of 5 mg ramipril and 6 mg piretanide administered separately and in combination were determined in a single blind, randomised, 3-period cross-over study in 24 healthy male volunteers. The peak plasma concentrations
Soizic Potier et al.
The European journal of neuroscience, 21(7), 1828-1836 (2005-05-05)
We have previously shown that exposure to the anti-cholinesterase eserine provokes interictal-like discharges in the CA3 area of hippocampal slices from adult rats in which a generalized seizure has been induced by pentylenetetrazole (PTZ) when immature (at 20 days). Such
R Prestel et al.
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, 115(Suppl I), 659-663 (2003-10-02)
The loop-diuretic piretanide was used to study the influence of pharmacological donor pretreatment on immediate postischemic function in a pig model of kidney transplantation based on the results of a clinical pilot study [4]. Following laparotomy, both kidneys were flushed

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