B1000000

Betamethasone

European Pharmacopoeia (EP) Reference Standard

• Sinónimos: 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16β-methylprednisolone
• Fórmula empírica (notación de Hill): C₂₂H₂₉FO₅
• Número de CAS: 378-44-9
• Peso molecular: 392.46
• Número MDL: MFCD00062969
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329773150
• NACRES: NA.24

Propiedades

• origen biológico: synthetic
• grado: pharmaceutical primary standard
• Agency: EP
• familia API: betamethasone
• envase: pkg of 60 mg
• fabricante / nombre comercial: EDQM
• condiciones de almacenamiento: protect from light
• color: white
• mp: 235-237 °C (lit.); 235.6 °C (456.1°F at 1013.0 hPa)
• solubilidad: water: slightly soluble 0.063 g/L at 37 °C
• densidad: 0.305 g/cm³ at 25 °C (77°F)
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• Condiciones de envío: ambient
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
• Clave InChI: UREBDLICKHMUKA-DVTGEIKXSA-N
• Información sobre el gen: human ... NR3C1(2908)

Descripción

Descripción general

Betamethasone, a synthetic glucocorticoid, belongs to the corticosteroid family of active pharmaceutical ingredients (APIs).

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Betamethasone EP reference standard may be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H360FD,H373
• Consejos de prudencia: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Repr. 1B - STOT RE 2
• Órganos de actuación: Liver,Kidney,Endocrine system
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable